Trio Role of Deep Eutectic Solvents in the Green Synthesis of 1,4-Dihydropyridine Synthesis via Hantzsch Reaction

被引：7

作者：

Kumar, Gobind ^{[1
]}

Bhargava, Gaurav ^{[1
]}

Kumar, Rupesh ^{[1
]}

机构：

[1] IKG Punjab Tech Univ, Dept Chem Sci, Kapurthala 144603, Punjab, India

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2023年 / 43卷 / 08期

关键词：

Deep eutectic solvent; green chemistry; Hantzsch reaction; 14-dihydropyridine; metal free catalysis; ONE-POT SYNTHESIS; EFFICIENT SYNTHESIS; DERIVATIVES; CATALYSTS; METRICS; POLYHYDROQUINOLINES; SYSTEMS;

D O I：

10.1080/10406638.2022.2133905

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Here, we have reported a novel deep eutectic solvent (DES) with tremendous activity for the synthesis of dihydropyridines. DESs have played a trio role in the reaction. It acts as a green catalyst, solvent, and in-situ substrate in this chemical reaction. This method offers various advantages such as metal-free catalysis, green solvent, high yields of the products, and short reaction time.

引用

页码：7238 / 7251

页数：14

共 50 条

[1] Green approach for synthesis of bioactive Hantzsch 1,4-dihydropyridine derivatives based on thiophene moiety via multicomponent reaction
Sharma, M. G.
Rajani, D. P.
Patel, H. M.
ROYAL SOCIETY OPEN SCIENCE, 2017, 4 (06):
[2] Synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives via Hantzsch reaction using nicotinic acid as a green and reusable catalyst
Davarpanah, Jamal
Ghahremani, Mahboubeh
Najafi, Ozhan
JOURNAL OF MOLECULAR STRUCTURE, 2019, 1177 : 525 - 535
[3] Dual solvent-catalyst role of deep eutectic solvents in Hantzsch dihydropyridine synthesis
Shaibuna, M.
Sreekumar, K.
SYNTHETIC COMMUNICATIONS, 2021, 51 (11) : 1742 - 1753
[4] A HANTZSCH 1,4-DIHYDROPYRIDINE SYNTHESIS PRODUCING AN UNUSUAL BY-PRODUCT
PATTERSON, JW
NELSON, JT
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1988, 25 (01) : 125 - 128
[5] Hantzsch 1,4-dihydropyridine synthesis in aqueous ethanol by visible light
Ghosh, Somnath
Saikh, Fond
Das, Jhantu
Pramanik, Arun Kumar
TETRAHEDRON LETTERS, 2013, 54 (01) : 58 - 62
[6] THE HANTZSCH 1,4-DIHYDROPYRIDINE SYNTHESIS AS A ROUTE TO BRIDGED PYRIDINE AND DIHYDROPYRIDINE CROWN ETHERS
KELLOGG, RM
VANBERGEN, TJ
VANDOREN, H
HEDSTRAND, D
KOOI, J
KRUIZINGA, WH
TROOSTWIJK, CB
JOURNAL OF ORGANIC CHEMISTRY, 1980, 45 (14): : 2854 - 2861
[7] Cobalt triflate catalyzed one-pot synthesis of fluorophore 1,4-dihydropyridine derivatives via Hantzsch reaction
Bagdi, Prasanta Ray
Basha, R. Sidick
Lal, Mohan
Misra, Rajkumar
Khan, Abu T.
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2013, 90 (10) : 1589 - 1598
[8] Green Synthesis of 1,4-Dihydropyridine Derivative in Water
Isomura, Shigeki
Horigome, Ami
Kubo, Kotaro
Yoshizawa, Yukari
Okuno, Yoshinori
Okayasu, Misaki
Azumaya, Isao
Sato, Yasuo
CHEMISTRYSELECT, 2018, 3 (11): : 3003 - 3005
[9] One-pot multi-component synthesis of 1,4-dihydropyridine derivatives in biocompatible deep eutectic solvents
Pednekar, Suhas
Bhalerao, Rahul
Ghadge, Nitin
JOURNAL OF CHEMICAL SCIENCES, 2013, 125 (03) : 615 - 621
[10] One-pot multi-component synthesis of 1,4-dihydropyridine derivatives in biocompatible deep eutectic solvents
SUHAS PEDNEKAR
RAHUL BHALERAO
NITIN GHADGE
Journal of Chemical Sciences, 2013, 125 : 615 - 621

← 1 2 3 4 5 →