Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements

被引：5

作者：

Johnson, Kara A. ^{[1
,2
]}

Dosenbach, Nico U. F. ^{[3
]}

Gordon, Evan M. ^{[4
]}

Welle, Cristin G. ^{[5
,6
]}

Wilkins, Kevin B. ^{[7
]}

Bronte-Stewart, Helen M. ^{[7
]}

Voon, Valerie ^{[8
]}

Morishita, Takashi ^{[9
]}

Sakai, Yuki ^{[10
,11
]}

Merner, Amanda R. ^{[12
]}

Lazaro-Munoz, Gabriel ^{[12
,13
]}

Williamson, Theresa ^{[14
]}

Horn, Andreas ^{[15
,16
,17
,18
,19
]}

Gilron, Ro'ee ^{[20
]}

O'Keeffe, Jonathan ^{[21
]}

Gittis, Aryn H. ^{[22
,23
]}

Neumann, Wolf-Julian ^{[17
,18
,19
]}

Little, Simon ^{[24
]}

Provenza, Nicole R. ^{[25
]}

Sheth, Sameer A. ^{[25
]}

Fasano, Alfonso ^{[26
,27
]}

Holt-Becker, Abbey B. ^{[28
]}

Raike, Robert S. ^{[28
]}

Moore, Lisa ^{[29
]}

Pathak, Yagna J. ^{[30
]}

Greene, David ^{[31
]}

Marceglia, Sara ^{[32
]}

Krinke, Lothar ^{[33
,34
]}

Tan, Huiling ^{[35
]}

Bergman, Hagai ^{[36
,37
]}

Poetter-Nerger, Monika ^{[38
]}

Sun, Bomin ^{[39
]}

Cabrera, Laura Y. ^{[40
,41
]}

McIntyre, Cameron C. ^{[42
,43
]}

Harel, Noam ^{[44
]}

Mayberg, Helen S. ^{[45
]}

Krystal, Andrew D. ^{[46
]}

Pouratian, Nader ^{[47
]}

Starr, Philip A. ^{[24
]}

Foote, Kelly D. ^{[1
,48
]}

Okun, Michael S. ^{[1
,2
]}

Wong, Joshua K. ^{[1
,2
]}

机构：

[1] Univ Florida, Norman Fixel Inst Neurol Dis, Gainesville, FL 32611 USA

[2] Univ Florida, Dept Neurol, Gainesville, FL 32611 USA

[3] Washington Univ, Sch Med, Dept Neurol, St Louis, MO USA

[4] Washington Univ, Sch Med, Dept Neurosci, St Louis, MO USA

[5] Univ Colorado, Sch Med, Dept Physiol & Biophys, Aurora, CO USA

[6] Univ Colorado, Sch Med, Dept Neurosurg, Aurora, CO USA

[7] Stanford Univ, Dept Neurol & Neurol Sci, Sch Med, Stanford, CA USA

[8] Univ Cambridge, Dept Psychiat, Cambridge, England

[9] Fukuoka Univ, Fac Med, Dept Neurosurg, Fukuoka, Japan

[10] ATR Brain Informat Commun Res Lab Grp, Kyoto, Japan

[11] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Psychiat, Kyoto, Japan

[12] Harvard Med Sch, Ctr Bioeth, Boston, MA USA

[13] Massachusetts Gen Hosp, Dept Psychiat, Boston, MA USA

[14] Massachusetts Gen Hosp, Dept Neurosurg, Boston, MA USA

[15] Harvard Med Sch, Brigham & Womens Hosp, Ctr Brain Circuit Therapeut, Dept Neurol, Boston, MA USA

[16] Harvard Med Sch, MGH Neurosurg & Ctr Neurotechnol & Neurorecovery, MGH Neurol Massachusetts Gen Hosp, Boston, MA USA

[17] Charite Univ Med Berlin, Movement Disorder & Neuromodulat Unit, Dept Neurol, Berlin, Germany

[18] Free Univ Berlin, Berlin, Germany

[19] Humboldt Univ, Berlin, Germany

[20] Rune Labs, San Francisco, CA USA

[21] Machine Med, London, England

[22] Carnegie Mellon Univ, Biol Sci, Pittsburgh, PA USA

[23] Carnegie Mellon Univ, Ctr Neural Basis Cognit, Pittsburgh, PA USA

[24] Univ Calif San Francisco, Weill Inst Neurosci, Dept Neurol Surg, San Francisco, CA USA

[25] Baylor Coll Med, Dept Neurosurg, Houston, TX USA

[26] Univ Toronto, Toronto Western Hosp UHN, Morton & Gloria Shulman Movement Disorders Clin, Edmond J Safra Program Parkinsons Dis,Div Neurol, Toronto, ON, Canada

[27] Krembil Brain Inst, Toronto, ON, Canada

[28] Medtronic Inc, Restorat Therapies Grp Implantables Res & Core Te, Minneapolis, MN USA

[29] Boston Sci Neuromodulat Corp, Valencia, CA USA

[30] Neuromodulat Div, Plano, TX USA

[31] NeuroPace Inc, Mountain View, CA USA

[32] Univ Trieste, Dept Engn & Architecture, Trieste, Italy

[33] Newronika SPA, Milan, Italy

[34] West Virginia Univ, Dept Neurosci, Morgantown, WV USA

[35] Univ Oxford, Med Res Council Brain Network Dynam Unit, Nuffield Dept Clin Neurosci, Oxford, England

[36] Hebrew Univ Jerusalem, Inst Med Res Israel Canada, Edmond & Lily Safar Ctr ELSC, Brain Res & Dept Med Neurobiol Physiol, Jerusalem, Israel

[37] Hadassah Kerem Med Ctr, Dept Neurosurg, Jerusalem, Israel

[38] Univ Med Ctr Hamburg Eppendorf, Dept Neurol, Hamburg, Germany

[39] Shanghai Jiao Tong Univ, Ruijin Hosp, Ctr Funct Neurosurg, Dept Neurosurg,Sch Med, Shanghai, Peoples R China

[40] Penn State Univ, Dept Engn Sci & Mech Philosophy & Bioeth, Neuroeth, State Coll, PA USA

[41] Penn State Univ, Rock Eth Inst, State Coll, PA USA

[42] Duke Univ, Dept Biomed Engn, Durham, NC USA

[43] Duke Univ, Dept Neurosurg, Durham, NC USA

[44] Univ Minnesota, Ctr Magnet Resonance Res, Dept Radiol, Minneapolis, MN USA

[45] Icahn Sch Med Mt Sinai, Dept Neurosurg Neurol Psychiat & Neurosci, New York, NY USA

[46] Univ Calif San Francisco, Dept Psychiat & Behav Sci, San Francisco, CA USA

[47] Univ Texas Southwestern Med Ctr Dallas, Dept Neurol Surg, Dallas, TX USA

[48] Univ Florida, Dept Neurosurg, Gainesville, FL USA

来源：

FRONTIERS IN HUMAN NEUROSCIENCE | 2024年 / 18卷

基金：

美国国家卫生研究院; 欧洲研究理事会; 英国医学研究理事会; 日本学术振兴会;

关键词：

deep brain stimulation (DBS); artificial intelligence; neuroethics; interventional psychiatry; adaptive DBS; Parkinson's disease; epilepsy; optogenetics; PARKINSONS-DISEASE; COORDINATED RESET; SYMPTOMS; MOTOR; GAIT;

D O I：

10.3389/fnhum.2024.1320806

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9-11, 2023 in Gainesville, Florida with the theme of "Pushing the Forefront of Neuromodulation". The keynote speaker was Dr. Nico Dosenbach from Washington University in St. Louis, Missouri. He presented his research recently published in Nature inn a collaboration with Dr. Evan Gordon to identify and characterize the somato-cognitive action network (SCAN), which has redefined the motor homunculus and has led to new hypotheses about the integrative networks underpinning therapeutic DBS. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers, and researchers (from industry and academia) can freely discuss current and emerging DBS technologies, as well as logistical and ethical issues facing the field. The group estimated that globally more than 263,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. This year's meeting was focused on advances in the following areas: cutting-edge translational neuromodulation, cutting-edge physiology, advances in neuromodulation from Europe and Asia, neuroethical dilemmas, artificial intelligence and computational modeling, time scales in DBS for mood disorders, and advances in future neuromodulation devices.

引用

页数：23

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