Antibacterial Potent of Acetylated and Non-Acetylated Clove Bud Essential Oils and Their Main Compounds

被引：5

作者：

Achraf, Abdou ^{[1
]}

Fatima Ezzahra, Maaghloud ^{[1
]}

Fatima Zahra, Moukhfi ^{[2
]}

Abdoullah, Bimoussa ^{[3
]}

Nour-Eddine, Chadli ^{[2
]}

Abdelhakim, Elmakssoudi ^{[1
]}

Jamal, Jamal Eddine ^{[1
]}

Mohamed, Dakir ^{[1
]}

机构：

[1] Hassan II Univ Casablanca, Fac Sci Ain Chock, Lab Organ Synth Extract & Valorizat, Casablanca, Morocco

[2] Hassan II Univ Casablanca, Lab Immunol & Biodivers, Fac Sci Ain Chock, Casablanca, Morocco

[3] Fac Sci Semlalia Marrakech, Lab Organ Synth & Phys Mol Chem, Marrakech, Morocco

来源：

CHEMISTRY & BIODIVERSITY | 2023年 / 20卷 / 04期

关键词：

Eugenia caryophyllata; essential oil; eugenol; isolation; antibacterial; EUGENOL;

D O I：

10.1002/cbdv.202201034

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Clove bud is a medicinal plant used traditionally in Asia for the treatment of various disease. Previously, Clove oil is a potential source of an antimicrobial compounds especially vis-a-vis bacterial pathogens. However, the compound responsible for this activity remains to be investigated. Essential oil (EO) clove, acetylated essential oil clove, eugenol, and acetyleugenol were evaluate as an antibacterial potential agent against Staphyloccocus aureus (SE), Escherichia coli (EC) and Pseudomonas aeruginosa (PA). Essential oil containing eugenol was extracted from buds of Eugenia caryophyllata commonly named clove (Syzygium aromaticum (L.) (Family Myrtaceae) by a simple hydrodistillation. The analysis of the essential oils (EOs) using gas chromatography-mass spectrometry (GC-MS) shows eugenol as the major constituent with 70.14 % of the total. The Eugenol was isolated from the EO using chemical treatment. Afterwards, the EO and eugenol were converted to acetylated EO and acetyleugenol, respectively using acetic anhydride. The antibacterial result revealed that all compounds showed a strong activity against the three strains. The Staphyloccocus aureus and Pseudomonas aeruginosa were extremely sensitive against eugenol with an inhibition diameters of 25 mm. The MIC values of eugenol versus S. aureus and P. aeruginosa were 0.58 and 2.32 mg/mL, respectively, while the MIB values were 2.32 mg/mL and 9.28 mg/mL.

引用

页数：7

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