Succinate aggravates pulmonary fibrosis through the succinate/SUCNR1 axis.

被引：0
|
作者：
Rajesh, Rishi [1 ]
Atallah, Reham [2 ]
Lanz, Ilse [1 ]
Platzer, Wolfgang [1 ]
Angiari, Stefano [3 ]
Marsh, Leigh [2 ]
Baernthaler, Thomas [1 ]
Heinemann, Akos [1 ]
机构：
[1] Med Univ Graz, Div Pharmacol, Otto Leowi Res Ctr, Graz, Austria
[2] Ludwig Boltzmann Inst Lung Vasc Res, Graz, Austria
[3] Med Univ Graz, Div Immunol, Otto Leowi Res Ctr, Graz, Austria
来源：
EUROPEAN RESPIRATORY JOURNAL | 2023年 / 62卷
关键词：
D O I：
10.1183/13993003.congress-2023.PA2359
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS
    Nunns, Geoffrey R.
    Vigneshwar, Navin
    Kelher, Marguerite R.
    Stettler, Gregory R.
    Gera, Lajos
    Reisz, Julie A.
    D'Alessandro, Angelo
    Ryon, Joshua
    Hansen, Kirk C.
    Gamboni, Fabia
    Moore, Ernest E.
    Peltz, Erik D.
    Cohen, Mitchell J.
    Jones, Kenneth L.
    Sauaia, Angela
    Liang, Xiayuan
    Banerjee, Anirban
    Ghasabyan, Arsen
    Chandler, James G.
    Rodawig, Sophia
    Jones, Carter
    Eitel, Andrew
    Hom, Patrick
    Silliman, Christopher C.
    ANNALS OF SURGERY, 2022, 276 (06) : E944 - E954
  • [22] Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle
    Abdelmoez, Ahmed M.
    Dmytriyeva, Oksana
    Zurke, Yasemin-Xiomara
    Trauelsen, Mette
    Marica, Alesandra A.
    Savikj, Mladen
    Smith, Jonathon A. B.
    Monaco, Claudia
    Schwartz, Thue W.
    Krook, Anna
    Pillon, Nicolas J.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2023, 324 (04): : E289 - E298
  • [23] SUCNR1 receptor mediates intestinal fibrosis
    Cosin-Roger, J.
    Ortiz-Masia, D.
    Macias-Ceja, D. C.
    Gisbert-Ferrandiz, L.
    Salvador, P.
    Hausmann, M.
    Rogler, G.
    Calatayud, S.
    Barrachina, M. D.
    JOURNAL OF CROHNS & COLITIS, 2018, 12 : S19 - S19
  • [24] Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling
    Trauelsen, Mette
    Hiron, Thomas K.
    Lin, Da
    Petersen, Jacob E.
    Breton, Billy
    Husted, Anna Sofie
    Hjorth, Siv A.
    Inoue, Asuka
    Frimurer, Thomas M.
    Bouvier, Michel
    O'Callaghan, Chris A.
    Schwartz, Thue W.
    CELL REPORTS, 2021, 35 (11):
  • [25] Acute Succinate Administration Increases Oxidative Phosphorylation and Skeletal Muscle Explosive Strength via SUCNR1
    Xu, Guli
    Yuan, Yexian
    Luo, Pei
    Yang, Jinping
    Zhou, Jingjing
    Zhu, Canjun
    Jiang, Qingyan
    Shu, Gang
    FRONTIERS IN VETERINARY SCIENCE, 2022, 8
  • [26] SUCNR1 AS A NEW PHARMACOLOGICAL TARGET FOR INTESTINAL FIBROSIS
    Cosin-Roger, J.
    Ortiz-Masia, D.
    Macias-Ceja, D.
    Gisbert, L.
    Salvador, P.
    Calatayud, S.
    Barrachina, M. D.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 123 : 42 - 42
  • [27] Baihu Jia Guizhi Decoction Improves Rheumatoid Arthritis Inflammation by Regulating Succinate/SUCNR1 Metabolic Signaling Pathway
    Chen, Huan
    Pan, Ting
    Liu, Panwang
    Wang, Ping
    Xu, Shijun
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 2019
  • [28] Succinate induces skeletal muscle fiber remodeling via SUCNR1 signaling (vol 20, e47892, 2019)
    Wang, Tao
    Xu, Ya-Qiong
    Yuan, Ye-Xian
    Xu, Ping-Wen
    Zhang, Cha
    Li, Fan
    Wang, Li-Na
    Yin, Cong
    Zhang, Lin
    Cai, Xing-Cai
    Zhu, Can-Jun
    Xu, Jing-Ren
    Liang, Bing-Qing
    Schaul, Sarah
    Xie, Pei-Pei
    Yue, Dong
    Liao, Zheng-Rui
    Yu, Lu-Lu
    Luo, Lv
    Zhou, Gan
    Yang, Jin-Ping
    He, Zhi-hui
    Du, Man
    Zhou, Yu-Ping
    Deng, Bai-Chuan
    Wang, Song-Bo
    Gao, Ping
    Zhu, Xiao-Tong
    Xi, Qian-Yun
    Zhang, Yong-Liang
    Shu, Gang
    Jiang, Qing-Yan
    EMBO REPORTS, 2021, 22 (06)
  • [29] Succinate induces skeletal muscle fiber remodeling via SUCNR1 signaling (vol 21, e47892, 2019)
    Wang, Tao
    Xu, Ya-Qiong
    Yuan, Ye-Xian
    Xu, Ping-Wen
    Zhang, Cha
    Li, Fan
    Wang, Li-Na
    Yin, Cong
    Zhang, Lin
    Cai, Xing-Cai
    Zhu, Can-Jun
    Xu, Jing-Ren
    Liang, Bing-Qing
    Schaul, Sarah
    Xie, Pei-Pei
    Yue, Dong
    Liao, Zheng-Rui
    Yu, Lu-Lu
    Luo, Lv
    Zhou, Gan
    Yang, Jin-Ping
    He, Zhi-Hui
    Du, Man
    Zhou, Yu-Ping
    Deng, Bai-Chuan
    Wang, Song-Bo
    Gao, Ping
    Zhu, Xiao-Tong
    Xi, Qian-Yun
    Zhang, Yong-Liang
    Shu, Gang
    Jiang, Qing-Yan
    EMBO REPORTS, 2020, 21 (05)
  • [30] miR-758 mediates oxLDL-dependent vascular endothelial cell damage by suppressing the succinate receptor SUCNR1
    Zhang, Hu
    Zheng, Jiajia
    Lin, Jiajia
    Chen, Jiulin
    Yu, Zhihua
    Chen, Chuan
    Liu, Te
    GENE, 2018, 663 : 1 - 8
12345