FDA Modernization Act 2.0 Paves the Way to Computational Biology and Clinical Trials in a Dish

被引：20

作者：

Ahmed, Syed Mukhtar ^{[1
,4
,6
]}

Shivnaraine, Rabindra V. ^{[2
,4
]}

Wu, Joseph C. ^{[1
,3
,5
]}

机构：

[1] Stanford Cardiovasc Inst, Stanford, CA USA

[2] Stanford Univ, Sch Med, Dept Mol & Cellular Physiol, Stanford, CA USA

[3] Stanford Univ, Sch Med, Dept Med, Div Cardiovasc Med, Stanford, CA USA

[4] Greenstone Biosci, Palo Alto, CA USA

[5] 265 Campus Dr G1120B, Stanford, CA 94305 USA

[6] 3160 Porter Dr,Suite 140, Palo Alto, CA 94304 USA

来源：

CIRCULATION | 2023年 / 148卷 / 04期

关键词：

animal use alternative; artificial intelligence; clinical trials as topic; drug development; drug discovery; induced pluripotent stem cells;

D O I：

10.1161/CIRCULATIONAHA.123.065585

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：309 / 311

页数：3

共 5 条

[1] Challenges and opportunities for the next generation of cardiovascular tissue engineering [J].

Cho, Sangkyun ;

Discher, Dennis E. ;

Leong, Kam W. ;

Vunjak-Novakovic, Gordana ;

Wu, Joseph C. .

NATURE METHODS, 2022, 19 (09) :1064-1071

[2] 2022 FDA approvals [J].

Mullard, Asher .

NATURE REVIEWS DRUG DISCOVERY, 2023, 22 (02) :83-88

[3] Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy [J].

Sayed, Nazish ;

Liu, Chun ;

Ameen, Mohamed ;

Himmati, Farhan ;

Zhang, Joe Z. ;

Khanamiri, Saereh ;

Moonen, Jan-Renier ;

Wnorowski, Alexa ;

Cheng, Linling ;

Rhee, June-Wha ;

Gaddam, Sadhana ;

Wang, Kevin C. ;

Sallam, Karim ;

Boyd, Jack H. ;

Woo, Y. Joseph ;

Rabinovitch, Marlene ;

Wu, Joseph C. .

SCIENCE TRANSLATIONAL MEDICINE, 2020, 12 (554)

[4] ELIXIRS, DILUENTS, AND THE PASSAGE OF THE 1938 FEDERAL FOOD, DRUG AND COSMETIC ACT [J].

WAX, PM .

ANNALS OF INTERNAL MEDICINE, 1995, 122 (06) :456-461

[5] Shifting machine learning for healthcare from development to deployment and from models to data [J].

Zhang, Angela ;

Xing, Lei ;

Zou, James ;

Wu, Joseph C. .

NATURE BIOMEDICAL ENGINEERING, 2022, 6 (12) :1330-1345

← 1 →