Prediction model based on radiomics and clinical features for preoperative lymphovascular invasion in gastric cancer patients

被引：5

作者：

Wang, Ping ^{[1
]}

Chen, Kaige ^{[1
]}

Han, Ying ^{[1
]}

Zhao, Min ^{[2
,3
]}

Abiyasi, Nanding ^{[1
]}

Peng, Haiyong ^{[1
]}

Yan, Shaolei ^{[1
]}

Shang, Jiming ^{[1
]}

Shang, Naijian ^{[1
]}

Meng, Wei ^{[1
]}

机构：

[1] Harbin Med Univ, Harbin Med Univ Canc Hosp, Radiol Dept, 150 Haping Rd, Harbin 150081, Heilongjiang, Peoples R China

[2] GE Healthcare, Pharmaceut Diagnost, Beijing, Peoples R China

[3] 1Tongji South Rd,Daxing Dist, Beijing 100176, Peoples R China

来源：

FUTURE ONCOLOGY | 2023年 / 19卷 / 23期

关键词：

contrast-enhanced computed tomography; gastric cancer; Lauren classification; lymphovascular invasion; radiomics; LYMPH-NODE METASTASIS; CT; ADENOCARCINOMA; PARAMETERS; MRI;

D O I：

10.2217/fon-2022-1025

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: We explored whether a model based on contrast-enhanced computed tomography radiomics features and clinicopathological factors can evaluate preoperative lymphovascular invasion (LVI) in patients with gastric cancer (GC) with Lauren classification. Methods: Based on clinical and radiomic characteristics, we established three models: Clinical + Arterial phase_Radcore, Clinical + Venous phase_Radcore and a combined model. The relationship between Lauren classification and LVI was analyzed using a histogram. Results: We retrospectively analyzed 495 patients with GC. The areas under the curve of the combined model were 0.8629 and 0.8343 in the training and testing datasets, respectively. The combined model showed a superior performance to the other models. Conclusion: CECT-based radiomics models can effectively predict preoperative LVI in GC patients with Lauren classification. Tweetable abstractContrast-enhanced computed tomography-based radiomics models can effectively predict the preoperative lymphovascular invasion status in patients with gastric cancer with Lauren classification.

引用

页码：1613 / 1626

页数：14

共 42 条

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