Polychlorinated dibenzo-p-dioxins and dibenzofurans and dioxin-like polychlorinated biphenyls in human milk from national human breast milk monitoring in 2016-2019 in China

Human breast milk monitoring programs were recommended to be carried out to assess human body burden to persis-tent organic pollutants and their temporal trends. Thus, we conducted a national survey during the period of 2016-2019 to determine PCDD/Fs and dl-PCBs in human breast milk from China. The total TEQ amounts in the upper bound (UB) was in the range of 1.97 to 15.1 pg TEQ g-1 fat with a geometric mean (GM) of 4.50 pg TEQ g-1 fat. 2,3,4,7,8-PeCDF, 1,2,3,7,8-PeCDD, and PCB-126 were more predominant contributors with the percentage contribution of 34.2 %, 17.9 %, and 17.4 %, respectively. By comparison with our previous monitoring results, the total TEQ in breast milk sample of the present study is statistically lower than that in 2011 with a reduction of 16.9 % in the average (p < 0.05), and comparable to that in 2007. The estimated GM of dietary intake of total TEQ for the breastfed was 25.4 pg TEQ kg-1 body weight day-1 that was higher than that of the adult. It is therefore worthy to make more efforts to reduce amounts of PCDD/Fs and dl-PCBs in breast milk and to continue monitoring to further observe if the amount of these chemicals continue to decrease.