Chronic chikungunya disease (CCD): clinical insights, immunopathogenesis and therapeutic perspectives

被引：2
作者：
Ng, W. H. [1 ,2 ,3 ]
Amaral, K. [4 ]
Javelle, E. [5 ,6 ,7 ,8 ]
Mahalingam, S. [1 ,2 ,3 ]
机构：
[1] Griffith Univ, Menzies Hlth Inst Queensland, Emerging Viruses Inflammat & Therapeut Grp, Gold Coast Campus,Parklands Dr, Southport, Qld 4222, Australia
[2] Griffith Univ, Global Virus Network GVN, Ctr Excellence Arboviruses, Gold Coast, Qld, Australia
[3] Griffith Univ, Sch Pharm & Med Sci, Gold Coast, Qld, Australia
[4] Fed Univ Cariri, Dept Hlth Sci, Barbalha, Ceara, Brazil
[5] Inst Rech Biomed Armees, Dept Microbiol & Malad Infect, Unite Parasitol & Entomol, Marseille, France
[6] Aix Marseille Univ, AP HM, VITROME, IRD,SSA, Marseille, France
[7] IHU Mediterranee Infect, Unit Infect Dis & Trop Med, Marseille, France
[8] Hop Instruct Armees Laveran, Serv Pathol Infect & Trop, Marseille, France
来源：
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE | 2024年 / 117卷 / 07期
关键词：
REGULATORY T-CELLS; VIRUS-INFECTION; CHRONIC ARTHRALGIA; ARTHRITIS;
D O I：
10.1093/qjmed/hcae028
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Chikungunya virus, an arthropod-borne pathogen is recognized by the World Health Organization as a top priority Emerging Infectious Disease and is ranked fourth in public health needs according to the Coalition for Epidemic Preparedness Innovations. Despite its substantial impact, as evidenced by an annual estimate of 120 274 disability-adjusted life years, our understanding of the chronic aspects of chikungunya disease remains limited. This review focuses on chronic chikungunya disease, emphasizing its clinical manifestations, immunopathogenesis, therapeutic options and disease burden.
引用
收藏
页码：489 / 494
页数：6
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