Society of Asian Academic Surgeons Combined Liver and Colon Resection of Synchronous Colorectal Liver Metastases at a Quaternary Center

被引:1
作者
Choong, Kevin [1 ]
Wong, Paul [1 ]
Thornblade, Lucas [1 ]
Melstrom, Kurt [1 ]
Lai, Lily [1 ]
Kaiser, Andreas [1 ]
Singh, Gagandeep [1 ]
Warner, Susanne G. [1 ]
Fakih, Marwan [1 ]
Fong, Yuman [1 ]
Melstrom, Laleh G. [1 ,2 ]
机构
[1] City Hope Comprehens Canc Ctr, Dept Med Oncol, Duarte, CA USA
[2] City Hope Comprehens Canc Ctr, Dept Surg, 1500 E Duarte Rd, Duarte, CA 91010 USA
关键词
Colorectal liver metastases; Hepatectomy; Synchronous resection; HIGH-VOLUME; CANCER; CHEMOTHERAPY; SURVIVAL; OUTCOMES;
D O I
10.1016/j.jss.2023.03.008
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction: Existing literature on the safety of combined liver and colorectal resections for synchronous colorectal liver metastases is mixed. Using a retrospective review of our institutional data, we aimed to show that combined colorectal and liver resections for synchronous metastases is both feasible and safe in a quaternary center. Methods: A retrospective review of combined resections for synchronous colorectal liver metastases at a quaternary referral center from 2015 to 2020 was completed. Clinicopathologic and perioperative data was collected. Univariate and multivariable analyses were performed to identify risk factors for major postoperative complications. Results: One hundred one patients were identified, with 35 undergoing major liver resections ( >= 3 segments) and 66 undergoing minor liver resections. The vast majority of patients (94%) received neoadjuvant therapy. There was no difference in postoperative major complications (Clavien-Dindo grade 3+) between major and minor liver resections (23.9% versus 12.1%, P = 0.16). On univariate analysis, Albumin-Bilirubin (ALBI) score >1 (P < 0.05) was predictive of major complication. However, on multivariable regression analysis, no factor was associated with significantly increased odds of major complication. Conclusions: This work demonstrates that with thoughtful patient selection, combined resection for synchronous colorectal liver metastases can be safely performed at a quaternary referral center.
引用
收藏
页码:252 / 260
页数:9
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