The role of eye banking with cell-based therapies

被引：1

作者：

Tran, Lillian T. ^{[1
]}

Li, Jennifer Y. ^{[1
,2
]}

机构：

[1] Univ Calif Sacramento, Dept Ophthalmol & Vis Sci, Davis Hlth, Sacramento, CA USA

[2] Univ Calif Sacramento, Ernest E Tschannen Eye Inst, Dept Ophthalmologyand Vis Sci, Davis Eye Ctr, 4860 YStreet, Sacramento, CA 95817 USA

来源：

CURRENT OPINION IN OPHTHALMOLOGY | 2023年 / 34卷 / 04期

关键词：

cell-based therapy; cultivated endothelial cells; cultured limbal epithelial transplantation; eye banking; limbal mesenchymal stem cell therapy; CORNEAL ENDOTHELIAL-CELLS; MESENCHYMAL STEM-CELLS; ROCK INHIBITOR; TISSUE; TRANSPLANTATION; KERATOPLASTY; RESTORATION; QUALITY; GRAFTS;

D O I：

10.1097/ICU.0000000000000962

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose of reviewCell-based therapies are an exciting new frontier in managing corneal diseases. The introduction of these novel therapies may provide new alternatives to corneal transplantation and decrease the dependence on donor corneal tissue. These changes have the potential to significantly impact eye banking in the future.Recent findingsThe current article reviews current research involving cell-based therapy for treating corneal disorders, including cultivated limbal stem cell transplantation, limbal mesenchymal stem cells for stromal regeneration, and the use of human-cultivated endothelial cells. We will look at barriers to the development and implementation of these therapies.As corneal surgery expands to include cell-based therapies; eye banks will need to redefine their role to support the everchanging landscape of corneal surgery and the decreased demand for corneal donor tissue.

引用

页码：334 / 338

页数：5

共 53 条

[1] Cellular therapy of the corneal stroma: a new type of corneal surgery for keratoconus and corneal dystrophies [J].

Alio del Barrio, Jorge L. ;

Alio, Jorge L. .

EYE AND VISION, 2018, 5

[2] Adipose-derived stem cells are a source for cell therapy of the corneal stroma [J].

Arnalich-Montiel, Francisco ;

Pastor, Silvia ;

Blazquez-Martinez, Alejandro ;

Fernandez-Delgado, Jorge ;

Nistal, Manuel ;

Alio, Jorge L. ;

De Miguel, Maria P. .

STEM CELLS, 2008, 26 (02) :570-579

[3] cGMP-Manufactured Human Induced Pluripotent Stem Cells Are Available for Pre-clinical and Clinical Applications [J].

Baghbaderani, Behnam Ahmadian ;

Tian, Xinghui ;

Neo, Boon Hwa ;

Burkall, Amy ;

Dimezzo, Tracy ;

Sierra, Guadalupe ;

Zeng, Xianmin ;

Warren, Kim ;

Kovarcik, Don Paul ;

Fellner, Thomas ;

Rao, Mahendra S. .

STEM CELL REPORTS, 2015, 5 (04) :647-659

[4] IS MY PRODUCT CAPABLE OF TUMOR FORMATION? [J].

Bailey, Alexander M. .

SCIENCE TRANSLATIONAL MEDICINE, 2012, 4 (147)

[5] Corneal supply and the use of technology to reduce its demand: A review [J].

Baird, Paul N. ;

Machin, Heather ;

Brown, Karl D. .

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2021, 49 (09) :1078-1090

[6]

Basu S, 2017, INVEST OPHTH VIS SCI, V58

[7] Human limbal biopsy-derived stromal stem cells prevent corneal scarring [J].

Basu, Sayan ;

Hertsenberg, Andrew J. ;

Funderburgh, Martha L. ;

Burrow, Michael K. ;

Mann, Mary M. ;

Du, Yiqin ;

Lathrop, Kira L. ;

Syed-Picard, Fatima N. ;

Adams, Sheila M. ;

Birk, David E. ;

Funderburgh, James L. .

SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (266)

[8] 13 Years of Cultured Limbal Epithelial Cell Therapy: A Review of the Outcomes [J].

Baylis, Oliver ;

Figueiredo, Francisco ;

Henein, Christin ;

Lako, Majlinda ;

Ahmad, Sajjad .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2011, 112 (04) :993-1002

[9] Mesenchymal Stem Cells in the Human Corneal Limbal Stroma [J].

Branch, Matthew James ;

Hashmani, Khurram ;

Dhillon, Permesh ;

Jones, D. Rhodri E. ;

Dua, Harminder Singh ;

Hopkinson, Andrew .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2012, 53 (09) :5109-5116

[10]

ClinicalTrials.gov, 2021, ID NCT00287391 EV CL

← 1 2 3 4 5 6 →