Recent Advances in the Synthesis of Dialkyl (Aryl) α-(Aryl/Heterocyclic/Heteroaryl-α-(Aryl/Heteroarylamino)Phosphonates

被引：2

作者：

Ali, Tarik E. ^{[1
]}

Assiri, Mohammed A. ^{[1
]}

Hussien, Mohamed ^{[1
,2
]}

Tantawy El Sayed, Ibrahim El ^{[2
]}

机构：

[1] King Khalid Univ, Fac Sci, Dept Chem, Abha 61421, Saudi Arabia

[2] Menoufia Univ, Fac Sci, Dept Chem, Shibin Al Kawm 32511, Egypt

来源：

CURRENT ORGANIC CHEMISTRY | 2023年 / 27卷 / 17期

关键词：

alpha-aminophosphonate; heterocycles; kabachnik-fields; pudovik; dialkyl; heterocyclic compounds; ALPHA-AMINOPHOSPHONATE DERIVATIVES; ONE-POT SYNTHESIS; KABACHNIK-FIELDS REACTION; SOLVENT-FREE SYNTHESIS; SILICO MOLECULAR DOCKING; BIOLOGICAL EVALUATION; HIGHLY EFFICIENT; CATALYZED SYNTHESIS; GREEN SYNTHESIS; SPECTRAL CHARACTERIZATION;

D O I：

10.2174/0113852728257284231012065956

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This review describes recent advances that are commonly applied in the synthesis of dialkyl (aryl) alpha-aminophosphonates containing heterocyclic compounds. The target structures are divided into three categories, which include alpha-aminophosphonic acids and their diesters bearing a heterocyclic or heteroaryl system at the alpha-carbon, nitrogen atom, or both. The synthetic protocols based on the Kabachnik-Fields and Pudovik reactions as the main pathways for the construction of these features, besides other miscellaneous methods. This review may be a useful resource for researchers and it will help them to work in this emerging research area.

引用

页码：1484 / 1503

页数：20

共 112 条

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