A "Leopard Man" Aspect on 18F-FDG PET/CT Revealing a VEXAS Syndrome

被引：4

作者：

Fagart, Alexandre ^{[1
]}

Quemeneur, Thomas ^{[2
]}

Collet, Guillaume ^{[1
]}

Demailly, Franck ^{[1
]}

Rousselin, Clementine ^{[2
]}

机构：

[1] Hosp Ctr Valenciennes, Dept Nucl Med, 114 Ave Desandrouin, F-59300 Valenciennes, France

[2] Hosp Ctr Valenciennes, Dept Nephrol & Internal Med, Valenciennes, France

来源：

CLINICAL NUCLEAR MEDICINE | 2023年 / 48卷 / 01期

关键词：

VEXAS syndrome; polyarteritis nodosa; myelodysplastic syndrome; FDG PET/CT; autoinflammatory diseases; BONE-MARROW INVOLVEMENT; MEDIATED FDG UPTAKE;

D O I：

10.1097/RLU.0000000000004443

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is an adult-onset autoinflammatory disease caused by somatic UBA1 mutations first described in 2020. Most of these patients met clinical criteria for an inflammatory syndrome (relapsing polychondritis, Sweet syndrome, polyarteritis nodosa, or giant-cell arteritis) or a hematologic condition (myelodysplastic syndrome or multiple myeloma) or both. We described here an FDG PET/CT "leopard man " appearance, with abnormal marrow recruitment the findings, in a 70-year-old man diagnosed with a VEXAS syndrome.

引用

页码：E33 / E34

页数：2

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