Risk factors of epilepsy secondary to viral encephalitis: A meta-analysis

被引：7
作者：
Yang, Qian [1 ]
Wei, Ben [2 ]
机构：
[1] Chengdu Med Coll, Affiliated Hosp 1, Dept Neurol, Chengdu 610500, Peoples R China
[2] Dujiangyan Shoujia Hosp, Dept Neurol, Chengdu 611830, Peoples R China
来源：
JOURNAL OF NEUROIMMUNOLOGY | 2023年 / 378卷
关键词：
Viral encephalitis; Epilepsy; Seizure; Risk factors; meta; -analysis; SEIZURES;
D O I：
10.1016/j.jneuroim.2023.578089
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Objective: To systematically evaluate the risk factors of post-encephalitis epilepsy (PEE).Methods: Systematic computerized searches of databases such as Cochrane Library, PubMed and EMBASE were performed. The meta-analysis of pooled odds ratios and 95% confidence intervals for PEE risk were calculated.Results: Sixteen studies with 2504 patients were included for meta-analysis. The results showed that PEE was associated with coma, seizure, status epilepticus, cranial MRI abnormality, focal EEG abnormality, and positive herpes simplex virus (HSV) in cerebrospinal fluid (CSF).Conclusion: Coma, seizures or status epilepticus, abnormal MRI and focal EEG, and HSV in CSF were the risk factors of PEE.
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页数：7
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