Critical review on the research of chemical structure, bioactivities, and mechanism of actions of Dendrobium officinale polysaccharide

被引：20
作者：
Lai, Cheuk-Hei [1 ]
Huo, Chu-Ying [1 ]
Xu, Jun [1 ]
Han, Quan-Bin [1 ]
Li, Li-Feng [1 ]
机构：
[1] Hong Kong Baptist Univ, Sch Chinese Med, Hong Kong, Peoples R China
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2024年 / 263卷
基金：
中国国家自然科学基金;
关键词：
Dendrobium officinale; Polysaccharides; Structure analysis; Bioactivity; Gut microbiota; TYPE-2; DIABETES-MELLITUS; GUT MICROBIOTA; IMMUNOMODULATORY ACTIVITY; METABOLISM; STEM; QUANTIFICATION; QUALITATION; RESISTANCE; DISORDERS; BUTYRATE;
D O I：
10.1016/j.ijbiomac.2024.130315
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Dendrobium officinale (Tie-Pi-Shi-Hu) is a precious traditional Chinese medicine (TCM). The principal active components are polysaccharides (DOP), which have a high potency in therapeutic applications. However, limitations in structure analysis and underlying mechanism investigation impede its further research. This review systemically and critically summarises current understanding in both areas, and points out the influence of starch impurities and the role of gut microbiota in DOP research. As challenges faced in studying natural polysaccharide investigations are common, this review contributes to a broader understanding of polysaccharides beyond DOP.
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页数：12
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