Cooperative Cu/Pd-Catalyzed 1,5-Boroacylation of Cyclopropyl-Substituted Alkylidenecyclopropanes

被引：3

作者：

Zeng, Hui-Hui ^{[1
]}

Wang, Yu-Qing ^{[1
]}

He, Yong-Yu ^{[1
]}

Zhong, Xiao-Ling ^{[1
]}

Li, Hongguang ^{[1
,2
]}

Ma, Ai-Jun ^{[1
]}

Peng, Jin-Bao ^{[1
]}

机构：

[1] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Guangdong, Peoples R China

[2] Wuyi Univ, Guangdong Prov Key Lab Large Anim Models Biomed, Jiangmen 529020, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 04期

关键词：

CROSS-COUPLING REACTIONS; ENANTIOSELECTIVE ARYLBORATION; STEREOSELECTIVE-SYNTHESIS; BORONIC ACIDS; IN-SITU; BOROACYLATION; AMINOBORATION; ALLENES; BIS(PINACOLATO)DIBORON; CARBOBORATION;

D O I：

10.1021/acs.joc.3c02670

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Cu/Pd-cocatalyzed 1,5-boroacylation of cyclopropyl-substituted ACPs with B2pin2 and acid chlorides has been developed. Using cyclopropyl-substituted ACPs as the starting material, a broad range of 1,5-boroacylated products with multiple functional groups was prepared in good yields with excellent regio- and stereoselectively. Both aromatic and aliphatic acid chlorides were tolerated in this reaction.

引用

页码：2637 / 2648

页数：12

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