Cooperative Cu/Pd-Catalyzed 1,5-Boroacylation of Cyclopropyl-Substituted Alkylidenecyclopropanes

被引：3
|
作者：
Zeng, Hui-Hui [1 ]
Wang, Yu-Qing [1 ]
He, Yong-Yu [1 ]
Zhong, Xiao-Ling [1 ]
Li, Hongguang [1 ,2 ]
Ma, Ai-Jun [1 ]
Peng, Jin-Bao [1 ]
机构：
[1] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Guangdong, Peoples R China
[2] Wuyi Univ, Guangdong Prov Key Lab Large Anim Models Biomed, Jiangmen 529020, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 04期
关键词：
CROSS-COUPLING REACTIONS; ENANTIOSELECTIVE ARYLBORATION; STEREOSELECTIVE-SYNTHESIS; BORONIC ACIDS; IN-SITU; BOROACYLATION; AMINOBORATION; ALLENES; BIS(PINACOLATO)DIBORON; CARBOBORATION;
D O I：
10.1021/acs.joc.3c02670
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Cu/Pd-cocatalyzed 1,5-boroacylation of cyclopropyl-substituted ACPs with B2pin2 and acid chlorides has been developed. Using cyclopropyl-substituted ACPs as the starting material, a broad range of 1,5-boroacylated products with multiple functional groups was prepared in good yields with excellent regio- and stereoselectively. Both aromatic and aliphatic acid chlorides were tolerated in this reaction.
引用
收藏
页码：2637 / 2648
页数：12
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