Improving anti-tumor CD8+T cell function through manipulating glutamine metabolism

被引：0
|
作者：
Fisher, Emilie L. [1 ]
Chi, Channing [1 ]
Suguira, Ayaka [1 ]
Madden, Matthew [1 ]
Rathmell, Jeffrey C. [1 ]
机构：
[1] Vanderbilt Univ, Med Ctr, Nashville, TN USA
来源：
JOURNAL OF IMMUNOLOGY | 2023年 / 210卷 / 01期
关键词：
D O I：
10.4049/jimmunol.210.Supp.157.05
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [21] YAP is a novel regulator of CD4+and CD8+T cell during activation, differentiation, and anti-tumor immunity
    Szeto, Gregory Lee
    Stampouloglou, Elena
    Cheng, Nan
    Federico, Anthony
    Slaby, Emily
    Linton, Jonathan
    Livingston, Natalie
    Schneck, Jonathan P.
    Monti, Stefano
    Varelas, Xaralabos
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [22] Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+T cells with enhanced effector function and anti-tumor response
    Yao, Cheng-cheng
    Sun, Rui-ming
    Yang, Yi
    Zhou, Hai-yan
    Meng, Zhou-wenli
    Chi, Rui
    Xia, Li-liang
    Ji, Ping
    Chen, Ying-ying
    Zhang, Guo-qing
    Sun, Hai-peng
    Lu, Shun
    Yang, Chen
    Wang, Ying
    CELL REPORTS, 2023, 42 (03):
  • [23] Neoantigen driven B cell and CD4+T follicular helper cell collaboration promotes robust anti-tumor CD8+T cell responses
    Cui, Can
    Joshi, Nikhil S.
    Craft, Joseph E.
    JOURNAL OF IMMUNOLOGY, 2021, 206
  • [24] An engineered IL-2 partial agonist promoted CD8+T cell stemness and anti-tumor efficacy
    Mo, Fei
    Yu, Zhiya
    Li, Peng
    Oh, Jangsuk
    Spolski, Rosanne
    Zhao, Liang
    Glassman, Caleb R.
    Yamamoto, Tori N.
    Chen, Yun
    Golebiowski, Filip M.
    Hermans, Dalton
    Marjri, Sonia S.
    Picton, Lora
    Liao, Wei
    Ren, Min
    Zhuang, Xiaoxuan
    Mitra, Suman
    Lin, Jian-Xin
    Gattinoni, Luca
    Powell, Jonathan D.
    Restifo, Nicholas P.
    Garcia, K. Christopher
    Leonard, Warren J.
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [25] Generating Potent Anti-Tumor CD62Lhigh CD8+T Cells for Adoptive Immunotherapy
    Yang, Shicheng
    Zhang, Ling
    Zheng, Zhili
    Park, Tristen
    Rosenberg, Steven A.
    Morgan, Richard A.
    JOURNAL OF IMMUNOTHERAPY, 2010, 33 (08) : 866 - 867
  • [26] Radiotherapy enhances newly infiltrating CD8+T cells into tumor and exert an anti-tumor effects.
    Yamashita, Kimihiro
    Fukuoka, Eiji
    Watanabe, Akihiro
    Agawa, Kyosuke
    Yamada, Kota
    Takiguchi, Gosuke
    Urakawa, Naoki
    Hasegawa, Hiroshi
    Yamamoto, Masashi
    Kanaji, Shingo
    Matsuda, Yoshiko
    Matsuda, Takeru
    Oshikiri, Taro
    Nakamura, Tetsu
    Suzuki, Satoshi
    Kakeji, Yoshihiro
    CANCER SCIENCE, 2021, 112 : 738 - 738
  • [27] YTHDF2 promotes tumor immune evasion by inhibiting CD8+T cell-mediated anti-tumor immunity
    Ma, Shoubao
    Xiao, Sai
    Caligiuri, Michael
    Yu, Jianhua
    JOURNAL OF IMMUNOLOGY, 2024, 212 (01):
  • [28] IL-18 enhances anti-tumor effect of memory CD8+T cells by augmenting metabolic activity and function
    Li, Wen
    Takai, Shinji
    Jing, Denan
    Yamanishi, Kyosuke
    Yamanishi, Hiromichi
    Okamura, Haruki
    CANCER SCIENCE, 2023, 114 : 385 - 385
  • [29] Lysophosphatidic acid modulates CD8 T cell immunosurveillance and metabolism to impair anti-tumor immunity
    Turner, Jacqueline A.
    Fredrickson, Malia A.
    D'Antonio, Marc
    Katsnelson, Elizabeth
    MacBeth, Morgan
    Van Gulick, Robert
    Chimed, Tugs-Saikhan
    McCarter, Martin
    D'Alessandro, Angelo
    Robinson, William A.
    Couts, Kasey L.
    Pelanda, Roberta
    Klarquist, Jared
    Tobin, Richard P.
    Torres, Raul M.
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [30] Obesity and CD8 T cell metabolism: Implications for anti-tumor immunity and cancer immunotherapy outcomes
    Turbitt, William J.
    Rosean, Claire Buchta
    Weber, K. Scott
    Norian, Lyse A.
    IMMUNOLOGICAL REVIEWS, 2020, 295 (01) : 203 - 219
12345