Afterglow bio-applications by utilizing triplet excited states of organic materials

被引：50
作者：
Fan, Yuanyuan [1 ]
Li, Qianqian [1 ]
Li, Zhen [1 ]
机构：
[1] Wuhan Univ, TaiKang Ctr Life & Med Sci, Hubei Key Lab Organ & Polymer Optoelect Mat, Dept Chem, Wuhan 430072, Peoples R China
来源：
SCIENCE CHINA-CHEMISTRY | 2023年 / 66卷 / 11期
基金：
中国国家自然科学基金;
关键词：
afterglow bioimaging; room temperature phosphorescence; triplet excited states; ROOM-TEMPERATURE-PHOSPHORESCENCE; MOLECULAR PACKING; PERSISTENT; DESIGN; LUMINESCENCE; LUMINOGENS; NANOPARTICLES; ENHANCEMENT;
D O I：
10.1007/s11426-023-1790-0
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Organic room temperature phosphorescence (RTP) materials with persistent afterglow exhibit good biocompatibility, high signal to noise ratio and time resolved imaging characteristics in bio-applications. Moreover, they can serve as hypoxia detection probes and photodynamic therapy agents for the sensitivity of triplet excitons toward oxygen in the surroundings. In this review, the recent progress of in vitro and in vivo afterglow bioimaging is presented by utilizing organic RTP materials. The strategies of molecular design and controlling methods of molecular packing were summarized, to prompt this new rising research field, with the emphasis on high intensity, ultralong lifetimes and red-shifted wavelengths of phosphorescence emission.
引用
收藏
页码：2930 / 2940
页数：11
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