Utility of the 21-month neurodevelopmental outcome for predicting neurodevelopmental impairment at 36 months for preterm infants <29 weeks gestation

被引:0
作者
Doucette, Stefani M. [1 ,2 ,3 ]
Tang, Selphee [2 ,3 ,4 ]
Kehler, Heather [2 ,3 ]
Creighton, Dianne [1 ]
Lodha, Abhay [1 ,2 ,3 ,5 ]
机构
[1] Univ Calgary, Foothills Med Ctr, Dept Pediat, Div Neonatol, Calgary, AB, Canada
[2] Alberta Hlth Serv, Calgary, AB, Canada
[3] Univ Calgary, Alberta Childrens Hosp, Dept Pediat, Neonatal Follow Up Clin, Calgary, AB, Canada
[4] Univ Calgary, Foothills Med Ctr, Dept Obstet & Gynecol, Calgary, AB, Canada
[5] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
关键词
CEREBRAL-PALSY; CHILDREN; BAYLEY; BIRTH; VALIDITY; CARE; HIP; AGE;
D O I
10.1038/s41372-023-01777-3
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: To determine the sensitivity and specificity of the 21-month neurodevelopmental outcome for predicting the presence of neurodevelopmental impairment at 36 months corrected age in a population of preterm infants under 29 weeks gestation.STUDY DESIGN: This is a retrospective observational cohort study. Preterm infants born under 29 weeks gestation who were followed up at both 18-21 months and 36 months corrected age with outcome data available were enrolled.RESULTS: Overall, 713 preterm infants <29 weeks gestation and were included in the final analysis. The specificity of the 21-month assessment for predicting neurodevelopmental impairment at 36 months corrected age was 66% (95% confidence interval[CI] 62-71%) with a positive predictive value of 61% (95% CI 56-66%).CONCLUSION: In preterm neonates born <29 weeks gestation, the 18-21 months corrected neurodevelopmental outcome had low specificity and positive predictive value for predicting the presence of neurodevelopmental impairment at 36 months corrected age.
引用
收藏
页码:1406 / 1412
页数:7
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