A case report of anti-NMDA receptor encephalitis in a young Egyptian female patient presenting with hyperreligiosity

被引:0
作者
Ibrahim, Hamdi [1 ]
Ali, Attaa [1 ]
Maksod, Safwat Abdel [1 ]
Khorshed, Magdy [1 ]
Wassef, Mona [1 ]
Alfishawy, Mostafa [1 ]
Rady, Hanan [1 ]
Mohamed, Adel [1 ]
Mahmod, Mohamed [1 ]
Ismael, Khaled [1 ]
Haron, Marwa [1 ]
Said, Suzan [1 ]
Adel, Riham [1 ]
Mohamed, Noha [1 ]
机构
[1] Egypt Minist Hlth & Populat Giza, Cairo, Egypt
关键词
Anti-NMDA receptor encephalitis; Hyperreligiosity;
D O I
10.1186/s43162-023-00204-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Anti-n-methyl-d-aspartate receptor (NMDAR) encephalitis is a form of autoimmune encephalitis that remains under-recognized due to the variability of the initial symptoms and can be misdiagnosed as viral encephalitis or other pathogens. This syndrome has been predominantly described in young females including personality changes, autonomic dysfunctions, and neurologic decompensation.About half of the cases have tumors, most commonly teratomas of the ovaries; another established trigger is herpes viral encephalitis, while the cause in other cases is unclear. In case of clinical suspicion, electroencephalogram and brain magnetic resonance imaging are useful, but lumbar puncture for cerebrospinal fluid analysis is used to confirm the diagnosis. Treatment for this disease includes immunosuppression, plasmapheresis, and tumor resection when indicated. In this case report, we present a case that presented with hyperreligiosity and proved to have autoimmune encephalitis.The main purpose of our case is to increase awareness regarding immune-mediated encephalitis, especially the anti-NMDAR encephalitis.
引用
收藏
页数:5
相关论文
共 13 条
[1]   Anti-N-methyl-D-aspartate receptor encephalitis: review of clinical presentation, diagnosis and treatment [J].
Barry, Helen ;
Byrne, Susan ;
Barrett, Elizabeth ;
Murphy, Kieran C. ;
Cotter, David R. .
BJPSYCH BULLETIN, 2015, 39 (01) :19-23
[2]   An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models [J].
Dalmau, Josep ;
Armangue, Thais ;
Planaguma, Jesus ;
Radosevic, Ma ;
Mannara, Francesco ;
Leypoldt, Frank ;
Geis, Christian ;
Lancaster, Eric ;
Titulaer, Maarten J. ;
Rosenfeld, Myrna R. ;
Graus, Francesc .
LANCET NEUROLOGY, 2019, 18 (11) :1045-1057
[3]   Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis [J].
Dalmau, Josep ;
Lancaster, Eric ;
Martinez-Hernandez, Eugenia ;
Rosenfeld, Myrna R. ;
Balice-Gordon, Rita .
LANCET NEUROLOGY, 2011, 10 (01) :63-74
[4]   Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies [J].
Dalmau, Josep ;
Gleichman, Amy J. ;
Hughes, Ethen G. ;
Rossi, Jeffrey E. ;
Peng, Xiaoyu ;
Lai, Meizan ;
Dessain, Scott K. ;
Rosenfeld, Mynna R. ;
Balice-Gordon, Rita ;
Lynch, David R. .
LANCET NEUROLOGY, 2008, 7 (12) :1091-1098
[5]   Anti-NMDA receptor encephalitis: report of ten cases and comparison with viral encephalitis [J].
Gable, M. S. ;
Gavali, S. ;
Radner, A. ;
Tilley, D. H. ;
Lee, B. ;
Dyner, L. ;
Collins, A. ;
Dengel, A. ;
Dalmau, J. ;
Glaser, C. A. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2009, 28 (12) :1421-1429
[6]   Delirious mania:: Clinical features and treatment response [J].
Karmacharya, Rakesh ;
England, Mary Lou ;
Ongur, Dost .
JOURNAL OF AFFECTIVE DISORDERS, 2008, 109 (03) :312-316
[7]   Anti-NMDA receptor encephalitis, autoimmunity, and psychosis [J].
Kayser, Matthew S. ;
Dalmau, Josep .
SCHIZOPHRENIA RESEARCH, 2016, 176 (01) :36-40
[8]   Anti-NMDA Receptor Encephalitis in Psychiatry [J].
Kayser, Matthew S. ;
Dalmau, Josep .
CURRENT PSYCHIATRY REVIEWS, 2011, 7 (03) :189-193
[9]   Neuroimaging in Rabies [J].
Laothamatas, Jiraporn ;
Sungkarat, Witaya ;
Hemachudha, Thiravat .
ADVANCES IN VIRUS RESEARCH: RESEARCH ADVANCES IN RABIES, VOL 79, 2011, 79 :309-327
[10]  
Minagar Alireza, 2017, INFLAMMATORY DISORDE, P177