Folic Acid Conjugated CuS Nanoprisms for Cancer Targeting and Photothermal Treatment

被引：4

作者：

Muhsen, Mustafa M. ^{[1
]}

Al-Jawad, Selma M. H. ^{[2
]}

Taha, Ali A. ^{[3
]}

机构：

[1] Univ Technol Baghdad, Laser & Optoelect Engn Dept, Baghdad, Iraq

[2] Univ Technol Baghdad, Sch Appl Sci, Appl Phys Dept, Baghdad, Iraq

[3] Univ Technol Baghdad, Sch Appl Sci, Biotechnol Dept, Baghdad, Iraq

来源：

PLASMONICS | 2024年 / 19卷 / 03期

关键词：

CuS nanoprism; Folic acid (FA); Two-phase colloidal method; Photothermal therapy; HYDROTHERMAL SYNTHESIS; BAND-GAP; NANOPARTICLES; NANOSTRUCTURES; TEMPERATURE; SURFACTANT; RESONANCE; ABLATION; STRAIN;

D O I：

10.1007/s11468-023-02072-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In this research, novel copper sulfide (CuS) nanoprisms with high surface area were prepared by two-phase colloidal method. The CuS nanoprisms were modified with folic acid as targeting molecules and used in cancer treatment as photothermal agent using NIR laser. FTIR analysis confirmed that the CuS have been synthesized and the FA was successfully conjugated the CuS nanoprisms. From UV-visible characterization, the prepared CuS nanoprisms have an absorption spectrum with two peaks appeared at UV-visible and near infrared region. The peak at UV-visible range greatly reduced when the folic acid conjugated CuS and the optical energy gap was decreased from 3.34 to 1.95 eV. The results of photothermal treatment indicated that the FA-CuS nanoprisms have high efficiency in photothermal therapy.

引用

页码：1359 / 1370

页数：12

共 50 条

[21] Folic Acid-Conjugated, SERS-Labeled Silver Nanotriangles for Multimodal Detection and Targeted Photothermal Treatment on Human Ovarian Cancer Cells
Boca-Farcau, Sanda
Potara, Monica
Simon, Timea
Juhem, Aurelie
Baldeck, Patrice
Astilean, Simion
MOLECULAR PHARMACEUTICS, 2014, 11 (02) : 391 - 399
[22] Folic acid and CuS conjugated graphene oxide: An efficient photocatalyst for explicit degradation of toxic dyes
Neelgund, Gururaj M.
Oki, Aderemi
APPLIED SURFACE SCIENCE, 2021, 566
[23] Hypoxia-responsive folic acid conjugated glycol chitosan nanoparticle for enhanced tumor targeting treatment
Jang, Eun Hyang
Shim, Man Kyu
Kim, Gye Lim
Kim, SooHyeon
Kang, Haewon
Kim, Jong-Ho
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 580
[24] Improved drug targeting of cancer cells by utilizing actively targetable folic acid-conjugated albumin nanospheres
Shen, Zheyu
Li, Yan
Kohama, Kazuhiro
Oneill, Brian
Bi, Jingxiu
PHARMACOLOGICAL RESEARCH, 2011, 63 (01) : 51 - 58
[25] EFFECTIVENESS OF CONJUGATED FORMS OF FOLIC ACID IN THE TREATMENT OF TROPICAL SPRUE
SUAREZ, RM
WELCH, AD
HEINLE, RW
SUAREZ, RM
NELSON, EM
JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1946, 31 (12): : 1294 - 1304
[26] Investigating the Potential of Conjugated Selenium Redox Folic Acid as a Treatment for Triple Negative Breast Cancer
Khandelwal, Soni
Boylan, Mallory
Kirsch, Gilbert
Spallholz, Julian E.
Gollahon, Lauren S.
ANTIOXIDANTS, 2020, 9 (02)
[27] A novel folic acid-conjugated TiO2-SiO2 photosensitizer for cancer targeting in photodynamic therapy
Feng, Xiaohui
Zhang, Shaokun
Wu, Hong
Lou, Xia
COLLOIDS AND SURFACES B-BIOINTERFACES, 2015, 125 : 197 - 205
[28] Folic Acid-conjugated Graphene Oxide loaded with Photosensitizers for Targeting Photodynamic Therapy
Huang, Peng
Xu, Cheng
Lin, Jing
Wang, Can
Wang, Xiansong
Zhang, Chunlei
Zhou, Xuejiao
Guo, Shouwu
Cui, Daxiang
THERANOSTICS, 2011, 1 : 240 - 250
[29] Folic acid as delivery vehicles: targeting folate conjugated fluorescent nanoparticles to tumors imaging
Ai, Jun
Xu, Yuanhong
Li, Dan
Liu, Zuojia
Wang, Erkang
TALANTA, 2012, 101 : 32 - 37
[30] Folic Acid-Conjugated Gold Nanostars for Computed Tomography Imaging and Photothermal/Radiation Combined Therapy
Hu, Ping
Hou, Xu
Yu, Xiaojun
Wei, Xuguo
Li, Yang
Yang, Dawei
Jiang, Xiaohong
ACS APPLIED BIO MATERIALS, 2021, 4 (06) : 4862 - 4871

← 1 2 3 4 5 →