Folic Acid Conjugated CuS Nanoprisms for Cancer Targeting and Photothermal Treatment

被引：4

作者：

Muhsen, Mustafa M. ^{[1
]}

Al-Jawad, Selma M. H. ^{[2
]}

Taha, Ali A. ^{[3
]}

机构：

[1] Univ Technol Baghdad, Laser & Optoelect Engn Dept, Baghdad, Iraq

[2] Univ Technol Baghdad, Sch Appl Sci, Appl Phys Dept, Baghdad, Iraq

[3] Univ Technol Baghdad, Sch Appl Sci, Biotechnol Dept, Baghdad, Iraq

来源：

PLASMONICS | 2024年 / 19卷 / 03期

关键词：

CuS nanoprism; Folic acid (FA); Two-phase colloidal method; Photothermal therapy; HYDROTHERMAL SYNTHESIS; BAND-GAP; NANOPARTICLES; NANOSTRUCTURES; TEMPERATURE; SURFACTANT; RESONANCE; ABLATION; STRAIN;

D O I：

10.1007/s11468-023-02072-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In this research, novel copper sulfide (CuS) nanoprisms with high surface area were prepared by two-phase colloidal method. The CuS nanoprisms were modified with folic acid as targeting molecules and used in cancer treatment as photothermal agent using NIR laser. FTIR analysis confirmed that the CuS have been synthesized and the FA was successfully conjugated the CuS nanoprisms. From UV-visible characterization, the prepared CuS nanoprisms have an absorption spectrum with two peaks appeared at UV-visible and near infrared region. The peak at UV-visible range greatly reduced when the folic acid conjugated CuS and the optical energy gap was decreased from 3.34 to 1.95 eV. The results of photothermal treatment indicated that the FA-CuS nanoprisms have high efficiency in photothermal therapy.

引用

页码：1359 / 1370

页数：12

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