Chemical constituents from Stellera chamaejasme L. and chemotaxonomic significance

被引:6
作者
Song, Qi [1 ,2 ,3 ,4 ]
Li, Shi-Fang [1 ,2 ,3 ,4 ]
Cheng, Zhuo-Yang [1 ,2 ,3 ,4 ]
Song, Shao-Jiang [1 ,2 ,3 ,4 ]
Huang, Xiao-Xiao [1 ,2 ,3 ,4 ]
机构
[1] Key Lab Computat Chem Based Nat Antitumor Drug Res, Shenyang, Liaoning, Peoples R China
[2] Engn Res Ctr Nat Med Act Mol Res & Dev, Shenyang, Liaoning, Peoples R China
[3] Key Lab Nat Bioact Cpds Discovery & Modificat, Shenyang, Peoples R China
[4] Shenyang Pharmaceut Univ, Sch Tradit Chinese Materia Medica, Shenyang 110016, Liaoning, Peoples R China
基金
中国国家自然科学基金;
关键词
Stellera chamaejasme L; Lignans; Coumarins; Diarylpentanes; Thymelaeaceae; Chemotaxonomic significance; SKIN-LESIONS; LIGNANS; BIOSYNTHESIS; DITERPENES; CANCER; DAPHNE; ROOTS;
D O I
10.1016/j.bse.2023.104602
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Fifteen compounds were isolated from the roots of Stellera chamaejasme L., including six lignans (1-6), one coumarin (7), five diarylpentanes (8-12), two penylpropanoids (13-14), and one alkaloid (15). The structures of these compounds were elucidated by extensive spectroscopic methods and comparison with literature data. This is the first report on the occurrence of compounds 1-3, 6, 8-9, 11, 13-15 in the family Thymelaeaceae, and compounds 4, 5, and 12 are the first reported in genus Stellera Linn. The network analysis of all isolated compounds was described to illustrate the significance of taxonomy. The presence of these congenetic lignans (1-6) may be used for the identification of Stellera genus.
引用
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页数:5
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