Pharmacological assessment of Co3O4, CuO, NiO and ZnO nanoparticles via antibacterial, anti-biofilm and anti-quorum sensing activities

被引：4

作者：

Junejo, Bindia ^{[1
]}

Eryilmaz, Mujde ^{[2
]}

Rizvanoglu, Suna Sibel ^{[2
]}

Palabiyik, Ismail Murat ^{[3
]}

Ghumro, Tania ^{[1
]}

Mallah, Arfana ^{[4
,5
]}

Solangi, Amber R. R. ^{[1
]}

Hyder, Syed Iqleem ^{[6
]}

Maleh, Hassan Karimi ^{[7
,8
,9
]}

Dragoi, Elena Niculina ^{[10
]}

机构：

[1] Univ Sindh Jamshoro, Natl Ctr Excellence Analyt Chem, Sindh 76080, Pakistan

[2] Ankara Univ, Fac Pharm, Dept Pharmaceut Microbiol, TR-06100 Ankara, Turkiye

[3] Ankara Univ, Fac Pharm, Dept Analyt Chem, TR-06100 Ankara, Turkiye

[4] Norwegian Univ Sci & Technol NTNU, Dept Chem, N-7491 Trondheim, Norway

[5] Univ Sindh, M A Kazi Inst Chem, Sindh 76080, Pakistan

[6] Govt Coll Univ, Dept Chem, Hyderabad, Pakistan

[7] Univ Elect Sci & Technol China, Sch Resources & Environm, Xiyuan Ave, Chengdu 611731, Peoples R China

[8] Quchan Univ Technol, Dept Chem Engn, Quchan, Iran

[9] Univ Johannesburg, Dept Chem Sci, POB 17011,Doornfontein Campus, ZA-2028 Johannesburg, South Africa

[10] Gheorghe Asachi Techn Univ, Cristofor Simionescu Fac Chem Engn & Environm Prot, Bld D Mangeron 73, Iasi 700050, Romania

来源：

WATER SCIENCE AND TECHNOLOGY | 2023年 / 87卷 / 11期

关键词：

antibacterial activity; antiquorum sensing; biofilm inhibition; metal oxide nanoparticles; OXIDE NANOPARTICLES; EXTRACT; EFFLUX;

D O I：

10.2166/wst.2023.150

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The resistance to many common antibiotics has dramatically increased disease-causing infections, especially those caused by pathogens. The creation of effective antimicrobial agents in the fight against infection has a new avenue of exploration thanks to nanotechnology. The combined effects of metal-based nanoparticles (NPs) are known to have intense antibacterial activities. However, a comprehensive analysis of some NPs regarding these activities is still unavailable. This study uses the aqueous chemical growth method to synthesize Co3O4, CuO, NiO and ZnO NPs. The prepared materials were characterized by scanning electron microscopy, transmission electron microscopy and X-ray diffraction techniques. The antibacterial activities of NPs were tested against Gram-positive and Gram-negative bacteria using the microdilution method, such as the minimum inhibitory concentration (MIC) method. The best MIC value among all the metal oxide NPs was 0.63 against Staphylococcus epidermidis ATCC12228 through ZnO NPs. The other metal oxide NPs also showed satisfactory MIC values against different test bacteria. In addition, the biofilm inhibition and antiquorum sensing activities of NPs were also examined. The present study presents a novel approach for the relative analysis of metal-based NPs in antimicrobial studies, demonstrating their potential for bacteria removal from water and wastewater.

引用

页码：2840 / 2851

页数：12