Preservation of human heart valves for replacement in children with heart valve disease: past, present and future

被引:4
作者
Peters, M. C. [1 ,2 ,3 ]
Kruithof, B. P. T. [2 ,4 ]
Bouten, C. V. C. [3 ,5 ]
Voets, I. K. [5 ,6 ]
van den Bogaerdt, A. [7 ]
Goumans, M. J. [2 ]
van Wijk, A. [1 ]
机构
[1] Univ Med Ctr Utrecht, Wilhelmina Childrens Hosp, Dept Pediat Cardiothorac Surg, NL-3584 EA Utrecht, Netherlands
[2] Leiden Univ, Med Ctr, Dept Cardiovasc Cell Biol, NL-2300 RC Leiden, Netherlands
[3] Eindhoven Univ Technol, Dept Biomed Engn, NL-5600 MB Eindhoven, Netherlands
[4] Leiden Univ, Med Ctr, Dept Cardiol, NL-2333 ZA Leiden, Netherlands
[5] Eindhoven Univ Technol, Inst Complex Mol Syst, NL-5600 MB Eindhoven, Netherlands
[6] Eindhoven Univ Technol, Dept Chem Engn & Chem, NL-5600 MB Eindhoven, Netherlands
[7] ETB BISLIFE Multi Tissue Ctr, Heart Valve Dept, NL-2333 BD Beverwijk, Netherlands
关键词
Congenital heart disease; Allograft heart valve; Valve replacement; Preservation; Tissue biobanking; AORTIC-VALVE; EXTRACELLULAR-MATRIX; CELL VIABILITY; ENDOTHELIAL-CELLS; CARDIAC-SURGERY; DONOR HEART; CRYOPRESERVATION; TISSUE; ALLOGRAFTS; VIVO;
D O I
10.1007/s10561-023-10076-2
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor allograft valves is the main treatment approach. However, none of the replacements provides a viable valve that can grow and/or adapt with the growth of the child leading to re-operation throughout life. In this study, we review the impact of donor valve preservation on moving towards a more viable valve alternative for valve replacements in children or young adults.
引用
收藏
页码:67 / 85
页数:19
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