Imaging of post-synaptic membrane trafficking in neuronal dendrites: progress, limitations, and new developments

被引:2
作者
Perrais, David [1 ]
Sposini, Silvia [1 ]
Angibaud, Julie [1 ]
机构
[1] Univ Bordeaux, CNRS, Interdisciplinary Inst Neurosci, Bordeaux, France
基金
英国惠康基金;
关键词
endocytosis; exocytosis; live cell fluorescence imaging; membrane; trafficking; synaptic plasticity; RECEPTOR ENDOCYTOSIS; AMPA RECEPTORS; FLUORESCENT PROTEIN; EXOCYTOSIS; FUSION; MECHANISMS; PLASTICITY; DYNAMICS; DOMAIN; ZONES;
D O I
10.1117/1.NPh.10.4.044404
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Membrane trafficking of post-synaptic cargo is a key determinant of synaptic transmission and synaptic plasticity. We describe here the latest developments in visualizing individual exocytosis and endocytosis events in neurons using pH-sensitive tags. We show how these tools help decipher the spatial and temporal regulation of membrane trafficking steps during synaptic plasticity.
引用
收藏
页数:6
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