Organoids in COVID-19: can we break the glass ceiling?

被引：0
作者：
Chau, Chiu Wang [1 ]
Sugimura, Ryohichi [1 ,2 ]
机构：
[1] Univ Hong Kong, Li Ka Shing Fac Med, Sch Biomed Sci, Pokfulam, 21 Sassoon Rd, Hong Kong 99077, Peoples R China
[2] Ctr Translat Stem Cell Biol, 17 Sci Pk W Ave,Sci Pk, Hong Kong 999077, Peoples R China
来源：
JOURNAL OF LEUKOCYTE BIOLOGY | 2024年 / 115卷 / 01期
关键词：
COVID-19; SARS-CoV-2; disease modeling; organoids; KIDNEY ORGANOIDS; SARS-COV-2; INFECTION; CEREBRAL ORGANOIDS; LUNG; CELLS; DISEASE; ACE2; INHIBITION; GENERATION; RESPONSES;
D O I：
10.1093/jleuko/qiad098
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
COVID-19 emerged in September 2020 as a disease caused by the virus SARS-CoV-2. The disease presented as pneumonia at first but later was shown to cause multisystem infections and long-term complications. Many efforts have been put into discovering the exact pathogenesis of the disease. In this review, we aim to discuss an emerging tool in disease modeling, organoids, in the investigation of COVID-19. This review will introduce some methods and breakthroughs achieved by organoids and the limitations of this system.
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收藏
页码：85 / 99
页数：15
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