Functionalization of 4-Hydroxy-6-methyl-2H-pyran-2-one via Modified Biginelli Reaction

被引：0
|
作者：
Kanevskaya, I. V. [1 ]
Pchelintseva, N. V. [1 ]
Fedotova, O. V. [1 ]
机构：
[1] Chernyshevsky Saratov State Univ, Inst Chem, Saratov 410012, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 59卷 / 04期
基金：
俄罗斯基础研究基金会;
关键词：
three-component condensation; thermal and microwave activation; 4-hydroxy-6-methyl-2H-pyran-2-one; aromatic aldehydes; urea; 3-[amino(aryl)methyl]-4-hydroxy-6-methyl-2H-pyran-2-ones; arylmethylene-bis-(4-hydroxy-6-methyl-2H-pyran-2-ones); 2-hydroxy-7-methyl-4-(3-nitrophenyl)-4; 4a-dihydro-5H-pyrano-[4; 3-d]pyrimidin-5-one; MECHANISM;
D O I：
10.1134/S107042802304005X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one-pot Biginelli reactions of 4-hydroxy-6-methyl-2H-pyran-2-one with aromatic aldehydes and urea have been studied under conventional thermal heating and microwave activation. Depending on the conditions, the products were previously unknown 3-[amino(aryl)methyl]-4-hydroxy-6-methyl-2H-pyran-2-ones, arylmethylenebis(4-hydroxy-6-methyl-2H-pyran-2-ones), or hybrid 2-hydroxy-7-methyl-4-(3-nitro-phenyl)-4,4a-dihydro-5H-pyrano[4,3-d]pyrimidin-5-one in the reaction with 3-nitrobenzaldehyde.
引用
收藏
页码：591 / 596
页数：6
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