Total neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma

被引：5

作者：

Clements, Hollie A. ^{[1
,2
]}

Underwood, Tim J. ^{[3
]}

Petty, Russell D. ^{[1
,2
,4
,5
]}

机构：

[1] Univ Dundee, Ninewells Hosp, Div Mol & Clin Med, Dundee, Scotland

[2] Univ Dundee, Med Sch, Dundee, Scotland

[3] Univ Southampton, Univ Hosp Southampton NHS Fdn Trust, Sch Canc Sci, Southampton, England

[4] NHS Tayside, Ninewells Hosp, Tayside Canc Ctr, Dundee, Scotland

[5] NHS Tayside, Med Sch, Dundee, Scotland

来源：

BRITISH JOURNAL OF CANCER | 2024年 / 130卷 / 01期

关键词：

ADVANCED RECTAL-CANCER; PEMBROLIZUMAB PLUS CHEMOTHERAPY; LOCALLY ADVANCED ESOPHAGEAL; PHASE-III TRIAL; PREOPERATIVE CHEMOTHERAPY; ADJUVANT CHEMOTHERAPY; OPEN-LABEL; GASTRIC-CANCER; PERIOPERATIVE CHEMOTHERAPY; IMPROVED SURVIVAL;

D O I：

10.1038/s41416-023-02458-w

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Adenocarcinoma of the oesophagus and gastro-oesophageal junction represent a large burden of cancer death in the Western World with an increasing incidence. In the past two decades, the overall survival of patients on a potentially curative treatment pathway has more than doubled due to the addition of perioperative oncological therapies to surgery. However, patients often fail to respond to oncological treatment or struggle to complete their treatment after surgery. In this review, we discuss the current evidence for total neoadjuvant therapy and options for assessment of treatment response.

引用

页码：9 / 18

页数：10

共 110 条

[11]

Bancewicz J, 2002, LANCET, V359, P1727

[12] Rectal Cancer, Version 2.2022 [J].

Benson, Al B., III ;

Venook, Alan P. ;

Al-Hawary, Mahmoud M. ;

Azad, Nilofer ;

Chen, Yi-Jen ;

Ciombor, Kristen K. ;

Cohen, Stacey ;

Cooper, Harry S. ;

Deming, Dustin ;

Garrido-Laguna, Ignacio ;

Grem, Jean L. ;

Gunn, Andrew ;

Hecht, J. Randolph ;

Hoffe, Sarah ;

Hubbard, Joleen ;

Hunt, Steven ;

Jeck, William ;

Johung, Kimberly L. ;

Kirilcuk, Natalie ;

Krishnamurthi, Smitha ;

Maratt, Jennifer K. ;

Messersmith, Wells A. ;

Meyerhardt, Jeffrey ;

Miller, Eric D. ;

Mulcahy, Mary F. ;

Nurkin, Steven ;

Overman, Michael J. ;

Parikh, Aparna ;

Patel, Hitendra ;

Pedersen, Katrina ;

Saltz, Leonard ;

Schneider, Charles ;

Shibata, David ;

Skibber, John M. ;

Sofocleous, Constantinos T. ;

Stotsky-Himelfarb, Eden ;

Tavakkoli, Anna ;

Willett, Christopher G. ;

Gregory, Kristina ;

Gurski, Lisa .

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2022, 20 (10) :1139-1167

[13] Long-course oxaliplatin-based preoperative chemoradiation versus 5 x 5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: results of a randomized phase III study [J].

Bujko, K. ;

Wyrwicz, L. ;

Rutkowski, A. ;

Malinowska, M. ;

Pietrzak, L. ;

Krynski, J. ;

Michalski, W. ;

Oledzki, J. ;

Kusnierz, J. ;

Zajac, L. ;

Bednarczyk, M. ;

Szczepkowski, M. ;

Tarnowski, W. ;

Kosakowska, E. ;

Zwolinski, J. ;

Winiarek, M. ;

Wisniowska, K. ;

Partycki, M. ;

Beczkowska, K. ;

Polkowski, W. ;

Stylinski, R. ;

Wierzbicki, R. ;

Bury, P. ;

Jankiewicz, M. ;

Paprota, K. ;

Lewicka, M. ;

Cisel, B. ;

Skorzewska, M. ;

Mielko, J. ;

Bebenek, M. ;

Maciejczyk, A. ;

Kapturkiewicz, B. ;

Dybko, A. ;

Hajac, L. ;

Wojnar, A. ;

Lesniak, T. ;

Zygulska, J. ;

Jantner, D. ;

Chudyba, E. ;

Zegarski, W. ;

Las-Jankowska, M. ;

Jankowski, M. ;

Kolodziejski, L. ;

Radkowski, A. ;

Zelazowska-Omiotek, U. ;

Czeremszynska, B. ;

Kepka, L. ;

Kolb-Sielecki, J. ;

Toczko, Z. ;

Fedorowicz, Z. .

ANNALS OF ONCOLOGY, 2016, 27 (05) :834-842

[14] Utility of Adjuvant Chemotherapy After Neoadjuvant Chemoradiation and Esophagectomy for Esophageal Cancer [J].

Burt, Bryan M. ;

Groth, Shawn S. ;

Sada, Yvonne H. ;

Farjah, Farhood ;

Cornwell, Lorraine ;

Sugarbaker, David J. ;

Massarweh, Nader N. .

ANNALS OF SURGERY, 2017, 266 (02) :297-304

[15]

Cancer Research UK, Oesophageal cancer statistics

[16] Induction FOLFOX and PET-Directed Chemoradiation for Locally Advanced Esophageal Adenocarcinoma [J].

Carr, Rebecca A. ;

Hsu, Meier ;

Harrington, Caitlin A. ;

Tan, Kay See ;

Bains, Manjit S. ;

Bott, Matthew J. ;

Ilson, David H. ;

Isbell, James M. ;

Janjigian, Yelena Y. ;

Maron, Steven B. ;

Park, Bernard J. ;

Rusch, Valerie W. ;

Sihag, Smita ;

Wu, Abraham J. ;

Jones, David R. ;

Ku, Geoffrey Y. ;

Molena, Daniela .

ANNALS OF SURGERY, 2023, 277 (03) :E538-E544

[17] Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer [J].

Cercek, Andrea ;

Roxburgh, Campbell S. D. ;

Strombom, Paul ;

Smith, J. Joshua ;

Temple, Larissa K. F. ;

Nash, Garrett M. ;

Guillem, Jose G. ;

Paty, Philip B. ;

Yaeger, Rona ;

Stadler, Zsofia K. ;

Seier, Kenneth ;

Gonen, Mithat ;

Segal, Neil H. ;

Reidy, Diane L. ;

Varghese, Anna ;

Shia, Jinru ;

Vakiani, Efsevia ;

Wu, Abraham J. ;

Crane, Christopher H. ;

Gollub, Marc J. ;

Garcia-Aguilar, Julio ;

Saltz, Leonard B. ;

Weiser, Martin R. .

JAMA ONCOLOGY, 2018, 4 (06)

[18] Clinical utility and applicability of circulating tumor DNA testing in esophageal cancer: a systematic review and meta-analysis [J].

Chidambaram, Swathikan ;

Markar, Sheraz R. .

DISEASES OF THE ESOPHAGUS, 2022, 35 (02)

[19] Long-course preoperative chemoradiation versus 5 x 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study [J].

Cisel, B. ;

Pietrzak, L. ;

Michalski, W. ;

Wyrwicz, L. ;

Rutkowski, A. ;

Kosakowska, E. ;

Cencelewicz, A. ;

Spalek, M. ;

Polkowski, W. ;

Jankiewicz, M. ;

Stylinski, R. ;

Bebenek, M. ;

Kapturkiewicz, B. ;

Maciejczyk, A. ;

Sadowski, J. ;

Zygulska, J. ;

Zegarski, W. ;

Jankowski, M. ;

Las-Jankowska, M. ;

Toczko, Z. ;

Zelazowska-Omiotek, U. ;

Kepka, L. ;

Socha, J. ;

Wasilewska-Tesluk, E. ;

Markiewicz, W. ;

Kladny, J. ;

Majewski, A. ;

Kapuscinski, W. ;

Suwinski, R. ;

Bujko, K. .

ANNALS OF ONCOLOGY, 2019, 30 (08) :1298-1303

[20] Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiation in patients with locally advanced rectal cancer: 7-year results of PRODIGE 23 phase III trial, a UNICANCER GI trial. [J].

Conroy, Thierry ;

Etienne, Pierre-Luc ;

Rio, Emmanuel ;

Evesque, Ludovic ;

Mesgouez-Nebout, Nathalie ;

Vendrely, Veronique ;

Artignan, Xavier ;

Bouche, Olivier ;

Boileve, Alice ;

Delaye, Matthieu ;

Gargot, Dany ;

Boige, Valerie ;

Bonichon-Lamichhane, Nathalie ;

Louvet, Christophe ;

De La Fouchardiere, Christelle ;

Morand, Clotilde ;

Pezzella, Veronica ;

Rullier, Eric ;

Castan, Florence ;

Borg, Christophe .

JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (17_SUPPL) :LBA3504-LBA3504

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