Interferon in chronic myeloid leukaemia: Is it useful for treatment-free remission?

被引：2
|
作者：
Breccia, Massimo [1 ]
Saglio, Giuseppe [2 ]
机构：
[1] Sapienza Univ, Dept Translat & Precis Med, Hematol, Rome, Italy
[2] Univ Turin, Dept Clin & Biol Sci, Turin, Italy
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2023年 / 202卷 / 06期
关键词：
chronic phase chronic myeloid leukemia; treatment-free remission; tyrosine kinase inhibitors; ALPHA;
D O I：
10.1111/bjh.19013
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The role of IFN alpha in chronic myeloid leukaemia patients who have achieved a deep molecular response (DMR) is still unknown. The study reported by Irani et al., which shows the prospective biological effects of the drug in combination with a second-generation tyrosine kinase inhibitor, pave the way for further clinical studies aimed at increasing the rate of DMR for a possible successful discontinuation. Commentary on: Irani et al. Immune modulation in chronic myeloid leukaemia patients treated with nilotinib and interferon-alpha. Br J Haematol 2023 (Online ahead of print). doi: 10.1111/bjh.18984.
引用
收藏
页码：1087 / 1088
页数：2
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