A review on the ecotoxicity of macrocyclic lactones and benzimidazoles on aquatic organisms

被引:4
作者
Muniz, Marta Silva [1 ]
Maia, Maria Eduarda Souza [1 ]
Araruna, Igor Caue Alves [1 ]
Martins, Rafael Xavier [1 ]
Rocha, Thiago Lopes [2 ]
Farias, Davi [1 ]
机构
[1] Univ Fed Paraiba, Lab Risk Assessment Novel Technol, Dept Mol Biol, BR-58050085 Joao Pessoa, Brazil
[2] Univ Fed Goias, Inst Trop Pathol & Publ Hlth, Lab Environm Biotechnol & Ecotoxicol, Goiania, Brazil
关键词
Agriculture; Aquatic toxicity; Daphnia magna; Emerging contaminants; Environmental risk assessment; Veterinary antiparasitics; ACUTE TOXICITY; VETERINARY PHARMACEUTICALS; SYNTHETIC PYRETHROIDS; ENVIRONMENTAL RISK; EMAMECTIN BENZOATE; DAPHNIA-MAGNA; IVERMECTIN; WATER; LIVESTOCK; BIOACCUMULATION;
D O I
10.1007/s11356-023-26354-1
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Despite its wide production and several applications, veterinary antiparasitics from macrocyclic lactones and benzimidazole classes have not received much scientific attention concerning their environmental risks. Thus, we aimed to provide insights into the state of the environmental research on macrocyclic lactone and benzimidazole parasiticides, emphasizing their toxicity to non-target aquatic organisms. We searched for relevant information on these pharmaceutical classes on PubMed and Web of Science. Our search yielded a total of 45 research articles. Most articles corresponded to toxicity testing (n = 29), followed by environmental fate (n = 14) and other issues (n = 2) of selected parasiticides. Macrocyclic lactones were the most studied chemical group (65% of studies). Studies were conducted mainly with invertebrate taxa (70%), with crustaceans being the most predominant group (n = 27; 51%). Daphnia magna was the most used species (n = 8; 15%). Besides, it also proved to be the most sensitive organism, yielding the lowest toxicity measure (EC50 0.25 mu g/L for decreased mobility after 48 h-abamectin exposure) reported. Moreover, most studies were performed in laboratory settings, tracking a limited number of endpoints (acute mortality, immobility, and community disturbance). We posit that macrocyclic lactones and benzimidazoles warrant coordinated action to understand their environmental risks.
引用
收藏
页码:54257 / 54279
页数:23
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