The dubious origin of beryllium toxicity

被引:20
作者
Elguero, Jose [1 ]
Alkorta, Ibon [1 ]
机构
[1] CSIC, Inst Quim Med, Juan Cierva 3, Madrid 28006, Spain
关键词
Beryllium; Toxicity; Coordination; Proteins; CATALYZED PROTON ABSTRACTION; HYDROGEN-BONDS; CARBON ACIDS; COORDINATION CHEMISTRY; COMPLEX; ION; DISPLACEMENT; INHIBITION; MECHANISM; MAGNESIUM;
D O I
10.1007/s11224-023-02130-2
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Four mechanisms have been proposed in the literature to explain beryllium toxicity; they can be divided in two groups of two mechanisms: (i) replacement type: models 1 and 2; (ii) addition type: models 3 and 4. At this moment is not possible to select the best model not even to establish if one of these models will be the ultimate mechanism of beryllium toxicity. However, it is important to know the still open discussion about something so important associated with one of the simplest elements of the periodic table.
引用
收藏
页码:391 / 398
页数:8
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