Investigating the place of sodium-glucose cotransporter-2 inhibitors and dual sodium-glucose cotransporter-1 and dual sodium-glucose cotransporter-2 inhibitors in heart failure therapy: a systematic review of the literature

被引：1

作者：

Mckenzie, Taylor ^{[1
,2
]}

Hale, Genevieve M. ^{[1
,2
]}

Miner, Amelia ^{[1
,2
]}

Colon, Jean Colon ^{[2
]}

Evins, Garrett ^{[1
,2
]}

Wade, Jasmine ^{[1
,2
]}

机构：

[1] Nova Southeastern Univ Barry, 11501 North Mil Trail, Palm Beach Gardens, FL 33410 USA

[2] Judy Silverman Coll Pharm, 11501 North Mil Trail, Palm Beach Gardens, FL 33410 USA

来源：

HEART FAILURE REVIEWS | 2024年 / 29卷 / 02期

关键词：

SGLT2; inhibitors; Heart failure; Cardiovascular mortality; Chronic kidney disease; Sequencing; SGLT2; INHIBITORS; DAPA-HF; DAPAGLIFLOZIN; ENALAPRIL; MORTALITY; SAFETY;

D O I：

10.1007/s10741-024-10388-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sodium-glucose cotransporter-2 inhibitors have been shown to have significant metabolic, renal, and atherosclerotic cardiovascular disease benefits. Recent randomized controlled trials have extended these benefits to patients with heart failure. In fact, the robust findings from these studies in patients with any type of heart failure have led to the incorporation of this drug class in currently updated evidence-based guidelines for this condition. However, given the novelty in utilizing these agents in heart failure, there is uncertainty regarding place in therapy and sequencing in treatment. As such, this review aims to summarize existing literature to guide practitioners regarding the use of these agents in the management of heart failure.

引用

页码：549 / 558

页数：10

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