Reevaluating First-line Therapies in Youth-Onset Type 2 Diabetes

被引：2
作者：
Chung, Stephanie T. [1 ,2 ,3 ]
Davis, Faith [1 ]
Patel, Tejal [2 ]
Mabundo, Lilian [1 ]
Estrada, Doris E. [2 ]
机构：
[1] Natl Inst Diabet & Digest & Kidney Dis, Sect Pediat Diabet Obes & Metab, NIH, Bethesda, MD 20892 USA
[2] Childrens Natl Hosp, Div Endocrinol & Diabet, Washington, DC 20010 USA
[3] Natl Inst Diabet & Digest & Kidney Dis, NIH, 10 Ctr Dr, Bld 10-CRC,RM 5-5942, Bethesda, MD 20892 USA
来源：
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 2024年 / 109卷 / 02期
基金：
美国国家卫生研究院;
关键词：
pediatric; type; 2; diabetes; medication; metformin; treatment;
D O I：
10.1210/clinem/dgad508
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The prevalence of youth-onset type 2 diabetes is growing worldwide and current first-line treatment with metformin and intensive behavior and lifestyle changes are suboptimal in over 50% of youth within 2 years of diagnosis. This perspective article is a call to action for reevaluation of existing strategies and critical appraisal of metformin as first-line therapy in youth-onset type 2 diabetes. Increased attention should be given to novel therapeutics approved in youth, including glucagon-like 1 receptor agonists, sodium glucose cotransporter-2, and sociocultural interventions that will promote diabetes self-management.
引用
收藏
页码：e870 / e872
页数：3
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