NanoBiT biosensors to investigate FFA4 signalling in adipocyte spheroids

被引:0
|
作者
Duncan, Ms Elaine [1 ]
Dow, Eden [1 ]
Hudson, Brian [1 ]
机构
[1] Univ Glasgow, Ctr Translat Pharmacol, Glasgow, Lanark, Scotland
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P0987
引用
收藏
页码:696 / 697
页数:2
相关论文
共 50 条
  • [1] Ursodesoxycholic acid is an FFA4 agonist and reduces hepatic steatosis via FFA4 signaling
    Xu, Fangfang
    Wang, Jun
    Wang, Pan
    Hou, Tao
    Zhou, Han
    Zhao, Yaopeng
    Wang, Jixia
    Liu, Yanfang
    Liang, Xinmiao
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2022, 917
  • [2] Label-free cell phenotypic study of FFA4 and FFA1 and discovery of novel agonists of FFA4 from natural products
    Xu, Fangfang
    Zhou, Han
    Liu, Xiumei
    Zhang, Xiuli
    Wang, Zhiwei
    Hou, Tao
    Wang, Jixia
    Qu, Lala
    Zhang, Pengyu
    Piao, Hailong
    Liang, Xinmiao
    RSC ADVANCES, 2019, 9 (26) : 15073 - 15083
  • [3] Development of a conformational biosensors to measure FFA4 receptor activation in 3D cultured adipocytes
    Vita, Luca
    BRITISH JOURNAL OF PHARMACOLOGY, 2023, 180 : 705 - 706
  • [4] Pharmacological evaluation of novel FFA4 compounds
    Euston, Eloise
    Alharbi, Abdulrahman G.
    Dong, Zhaoyang
    Prihandoko, Rudi
    Tobin, Andrew
    Milligan, Graeme
    BRITISH JOURNAL OF PHARMACOLOGY, 2020, 177 (11) : 2490 - 2490
  • [5] Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist
    Sparks, Steven M.
    Aquino, Christopher
    Banker, Pierette
    Collins, Jon L.
    Cowan, David
    Diaz, Caroline
    Dock, Steven T.
    Hertzog, Donald L.
    Liang, Xi
    Swiger, Erin D.
    Yuen, Josephine
    Chen, Grace
    Jayawickreme, Channa
    Moncol, David
    Nystrom, Christopher
    Rash, Vincent
    Rimele, Thomas
    Roller, Shane
    Ross, Sean
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (05) : 1278 - 1283
  • [6] Inverse agonism of the FFA4 free fatty acid receptor controls both adipogenesis and mature adipocyte function
    Alshammari, W. S.
    Duncan, E. M.
    Vita, L.
    Kenawy, M.
    Dibnah, B.
    Wabitsch, M.
    Gould, G. W.
    Hudson, B. D.
    CELLULAR SIGNALLING, 2025, 131
  • [7] Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases
    Christiansen, Elisabeth
    Watterson, Kenneth R.
    Stocker, Claire J.
    Sokol, Elena
    Jenkins, Laura
    Simon, Katharina
    Grundmann, Manuel
    Petersen, Rasmus K.
    Wargent, Edward T.
    Hudson, Brian D.
    Kostenis, Evi
    Ejsing, Christer S.
    Cawthorne, Michael A.
    Milligan, Graeme
    Ulven, Trond
    BRITISH JOURNAL OF NUTRITION, 2015, 113 (11) : 1677 - 1688
  • [8] Pharmacological Evaluation of Novel FFA4 Compounds.
    Euston, Eloise
    Dong, Zhaoyang
    Alharbi, Abdulrahman Ghali M.
    Prihandoko, Rudi
    Milligan, Graeme
    Tobin, Andrew
    BRITISH JOURNAL OF PHARMACOLOGY, 2021, 178 (02) : 431 - 432
  • [9] Targeting FFA1 and FFA4 receptors in cancer-induced cachexia
    Freitas, Raquel D. S.
    Muradas, Thais C.
    Dagnino, Ana Paula A.
    Rost, Fernanda L.
    Costa, Kesiane M.
    Venturin, Gianina T.
    Greggio, Samuel
    da Costa, Jaderson C.
    Campos, Maria M.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2020, 319 (05): : E877 - E892
  • [10] Understanding the appetite modulation pathways: The role of the FFA1 and FFA4 receptors
    Freitas, Raquel D. S.
    Campos, Maria M.
    BIOCHEMICAL PHARMACOLOGY, 2021, 186