Disseminated Bacillus Calmette-Guérin Infection with Rhabdomyolysis, Acute Kidney Injury, and Interstitial Pneumonia after Bacillus Calmette-Guérin Intravesical Instillation Therapy

被引：1

作者：

Sakurai, Yuki ^{[1
]}

Furuto, Yoshitaka ^{[1
]}

Saito, Takahiro ^{[1
]}

Namikawa, Akio ^{[1
]}

Takahashi, Hiroko ^{[1
]}

Shibuya, Yuko ^{[1
]}

机构：

[1] NTT Med Ctr Tokyo, Dept Hypertens & Nephrol, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2023年 / 62卷 / 24期

关键词：

BCG intravesical instillation therapy; BCG infection; bladder cancer; rhabdomyolysis; acute kidney injury; interstitial pneumonia; CALMETTE-GUERIN BCG; HYPERSENSITIVITY PNEUMONITIS; PULMONARY COMPLICATIONS; IMMUNOTHERAPY; CARCINOMA; DIAGNOSIS; SERIES;

D O I：

10.2169/internalmedicine.1413-22

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 79-year-old man experienced a fever and immobility after receiving 6 doses of Bacillus Calmette-Guerin (BCG) intravesical instillation therapy for bladder tumor. Rhabdomyolysis and acute kidney injury occurred; therefore, hemodialysis was performed. His kidney function was restored. However, he exhibited an inflammatory reaction that was resistant to broad-spectrum antibiotics and eventually developed interstitial pneumonia. Corticosteroid treatment partially relieved the symptoms of interstitial pneumonia, although disuse syndrome persisted. He was diagnosed with disseminated BCG infection through sputum culture. BCG infection shows various symptoms and is difficult to diagnose microbiologically. It should be suspected when systemic symptoms occur after BCG intravesical instillation therapy.

引用

页码：3707 / 3712

页数：6

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