Research Progress of Plant Active Ingredients in Pharmaceutical Cocrystal

被引：3

作者：

Wang, Zimeng ^{[1
]}

Shang, Hongzhou ^{[2
]}

Gao, Linghuan ^{[3
]}

Qiao, Ning ^{[2
]}

机构：

[1] North China Univ Sci & Technol, Coll Pharm, Tangshan 063210, Peoples R China

[2] North China Univ Sci & Technol, Coll Mat Sci & Engn, Tangshan 063210, Peoples R China

[3] North China Univ Sci & Technol, Coll Basic Med Sci, Tangshan 063210, Peoples R China

来源：

CURRENT DRUG DELIVERY | 2023年 / 20卷 / 10期

关键词：

Herbal ingredients; pharmaceutical cocrystals; properties solubility; bioavailability; medicinal; API's; ORAL BIOAVAILABILITY; CRYSTAL-STRUCTURES; SOLUBILITY; MYRICETIN; ARTEMISININ; KAEMPFEROL; INSIGHTS; DESIGN; ACIDS;

D O I：

10.2174/1567201819666220820115950

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The disadvantages of active ingredients extracted from medicinal plants due to poor solubility in the body and low bioavailability limit their clinical application. Pharmaceutical cocrystal as a new type of drug in solid form has attracted the attention of researchers. This article reviews the effects of cocrystal in various poorly soluble herbal active ingredients of medicinal plants on their physicochemical properties and biological properties and provides references for the application of pharmaceutical cocrystal in poorly soluble active compounds of medicinal plants.

引用

页码：1405 / 1424

页数：20

共 50 条

[41] Dissolution enhancement of active pharmaceutical ingredients by therapeutic deep eutectic systems [J].

Aroso, Ivo M. ;

Silva, Joao C. ;

Mano, Francisca ;

Ferreira, Ana S. D. ;

Dionisio, Madalena ;

Sa-Nogueira, Isabel ;

Barreiros, Susana ;

Reis, Rui L. ;

Paiva, Alexandre ;

Duarte, Ana Rita C. .

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2016, 98 :57-66

[42] The A Priori Design and Selection of Ionic Liquids as Solvents for Active Pharmaceutical Ingredients [J].

Kunov-Kruse, Andreas J. ;

Weber, Cameron C. ;

Rogers, Robin D. ;

Myerson, Allan S. .

CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (23) :5498-5508

[43] Deep Eutectic Solvents as Catalysts in the Synthesis of Active Pharmaceutical Ingredients and Precursors [J].

Falcini, Chiara ;

de Gonzalo, Gonzalo .

CATALYSTS, 2024, 14 (02)

[44] Amidation by reactive extrusion for the synthesis of active pharmaceutical ingredients teriflunomide and moclobemide [J].

Lavayssiere, Matthieu ;

Lamaty, Frederic .

CHEMICAL COMMUNICATIONS, 2023, 59 (23) :3439-3442

[45] A pharmaceutical cocrystal with potential anticancer activity [J].

Saha, Rajat ;

Sengupta, Suman ;

Dey, Sanjoy Kumar ;

Steele, Ian M. ;

Bhattacharyya, Arindam ;

Biswas, Susobhan ;

Kumar, Sanjay .

RSC ADVANCES, 2014, 4 (90) :49070-49078

[46] Cocrystal Systems of Pharmaceutical Interest: 2011 [J].

Brittain, Harry G. .

CRYSTAL GROWTH & DESIGN, 2012, 12 (11) :5823-5832

[47] Pharmaceutical Cocrystal: An Antique and Multifaceted Approach [J].

Panzade, Prabhakar S. ;

Shendarkar, Giridhar R. .

CURRENT DRUG DELIVERY, 2017, 14 (08) :1097-1105

[48] Cocrystal Systems of Pharmaceutical Interest: 2010 [J].

Brittain, Harry G. .

CRYSTAL GROWTH & DESIGN, 2012, 12 (02) :1046-1054

[49] Prodrug ionic liquids: functionalizing neutral active pharmaceutical ingredients to take advantage of the ionic liquid form [J].

Cojocaru, O. Andreea ;

Bica, Katharina ;

Gurau, Gabriela ;

Narita, Asako ;

McCrary, Parker D. ;

Shamshina, Julia L. ;

Barber, Patrick S. ;

Rogers, Robin D. .

MEDCHEMCOMM, 2013, 4 (03) :559-563

[50] Influence of Process Parameters on the Heterogeneous Nucleation of Active Pharmaceutical Ingredients onto Excipients [J].

Bueno, Raquel Arribas ;

Crowley, Clare M. ;

Hodnett, Benjamin K. ;

Hudson, Sarah ;

Davern, Peter .

ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2017, 21 (04) :559-570

← 1 2 3 4 5 →