Polysaccharide-based hydrogel promotes skin wound repair and research progress on its repair mechanism

被引:26
作者
Zhang, Shuai [1 ]
Liu, Hongyuan [1 ]
Li, Wei [1 ,2 ]
Liu, Xinglong [3 ]
Ma, Lina
Zhao, Ting [3 ]
Ding, Qiteng [1 ]
Ding, Chuanbo [3 ]
Liu, Wencong [1 ,4 ]
机构
[1] Jilin Agr Univ, Coll Chinese Med Mat, Changchun 130118, Peoples R China
[2] Jilin Agr Univ, Coll Life Sci, Engn Res Ctr Chinese Minist Educ Bioreactor & Phar, Changchun 130118, Peoples R China
[3] Jilin Agr Sci & Technol Coll, Coll Tradit Chinese Med, Jilin 132101, Peoples R China
[4] Wuzhou Univ, Sch Food & Pharmaceut Engn, Wuzhou 543003, Peoples R China
关键词
Skin damage; Skin repair; Polysaccharide-based hydrogel; Traditional Chinese medicine polysaccharide; Collagen deposition; DRUG-DELIVERY; HYALURONIC-ACID; IN-VIVO; INJECTABLE HYDROGELS; GREEN HYDROGELS; PECTIN; CHITOSAN; DESIGN; ANTIBACTERIAL; NANOPARTICLES;
D O I
10.1016/j.ijbiomac.2023.125949
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Polysaccharides, being a natural, active, and biodegradable polymer, have garnered significant attention due to their exceptional properties. These properties make them ideal for creating multifunctional hydrogels that can be used as wound dressings for skin injuries. Polysaccharide hydrogel has the ability to both simulate the natural extracellular matrix, promote cell proliferation, and provide a suitable environment for wound healing while protecting it from bacterial invasion. Polysaccharide hydrogels offer a promising solution for repairing damaged skin. This review provides an overview of the mechanisms involved in skin damage repair and emphasizes the potential of polysaccharide hydrogels in this regard. For different skin injuries, polysaccharide hydrogels can play a role in promoting wound healing. However, we still need to conduct more research on polysaccharide hydrogels to provide more possibilities for skin damage repair.
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收藏
页数:15
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