Validating the Mild Behavioral Impairment Checklist in a Cognitive Clinic: Comparisons With the Neuropsychiatric Inventory Questionnaire

被引：47
作者：
Hu, Sophie [1 ,2 ]
Patten, Scott [1 ,2 ,4 ,5 ]
Charlton, Anna [3 ]
Fischer, Karyn [2 ]
Fick, Gordon [1 ,5 ]
Smith, Eric E. [1 ,2 ,3 ]
Ismail, Zahinoor [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
[2] Univ Calgary, Hotchkiss Brain Inst, 3280 Hosp Dr NW,TRW Bldg 1st Floor, Calgary, AB T2N 4Z6, Canada
[3] Univ Calgary, Dept Clin Neurosci, Calgary, AB, Canada
[4] Univ Calgary, Dept Psychiat, Calgary, AB, Canada
[5] Univ Calgary, OBrien Inst Publ Hlth, Calgary, AB, Canada
来源：
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY | 2023年 / 36卷 / 02期
关键词：
Alzheimer's disease; mild cognitive impairment; neuropsychology; cognitive decline; behavior; ALZHEIMERS-DISEASE; DEMENTIA RISK; SYMPTOMS; ASSOCIATION; PREVALENCE; CONSENSUS; DECLINE; NEURODEGENERATION; MANIFESTATIONS; PSYCHOSIS;
D O I：
10.1177/08919887221093353
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Objective To compare the utility of the Mild Behavioral Impairment-Checklist (MBI-C) and Neuropsychiatric Inventory Questionnaire (NPI-Q) to capture NPS in subjective cognitive decline (SCD), mild cognitive impairment (MCI), and dementia. Methods In this cross-sectional memory clinic study, linear regression models compared MBI-C (n = 474) and NPI-Q (n = 1040) scores in relation to Montreal Cognitive Assessment (MoCA) score. Results MBI prevalence was 37% in subjective cognitive decline, 54% in mild cognitive impairment, and 62% in dementia. Worse diagnostic status was associated with higher MBI-C and NPI-Q score (P < .001), lower MoCA (P < .001), and greater age (P < .001). Higher MBI-C (beta -.09; 95% CI -.13, -.05) and NPI-Q (beta -.17; 95% CI -.23, -.10) scores were associated with lower MoCA scores, with psychosis most strongly associated (beta -1.11; 95% CI -1.56, -.65 vs beta -1.14; 95% CI -1.55, -.73). Conclusions The MBI-C captures global and domain-specific NPS across cognitive stages. Both the MBI-C and NPI-Q have utility in characterizing NPS.
引用
收藏
页码：107 / 120
页数：14
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