Localized pleural mesothelioma in a dog

被引:1
作者
Inanaga, Minori [1 ]
Yoneji, Wakana [2 ]
Ozaki, Kiyokazu [1 ]
机构
[1] Setsunan Univ, Fac Pharmaceut Sci, Lab Pathol, 45-1 Nagaotohgecho, Hirakata, Osaka 5730101, Japan
[2] Nara Anim Referral Clin, 5-20-7 Mitsugarasu, Nara 6310061, Japan
关键词
calretinin; dog; localized mesothelioma; pleural mesothelioma; Wilms' tumour gene 1; SCLEROSING PERITONEAL MESOTHELIOMA; IMMUNOHISTOCHEMISTRY; DIFFERENTIATION; DIAGNOSIS; TUMORS;
D O I
10.1016/j.jcpa.2023.09.006
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Malignant mesotheliomas with localized growth are extremely rare in dogs. A 9-year-old male dog presented with a localized tumour that originated from the parietal pleura and had polypoid growth in the thoracic cavity. Histological examination revealed that the tumour consisted of tubular formations with scattered cysts and minimal papillary growth pattern. Neoplastic cells were immunopositive for mesothelial markers (calretinin and Wilms' tumour gene 1) and negative for carcinoma markers (thyroid transcription factor 1 and tumour protein 63). The animal was alive with no recurrence or metastasis/ dissemination 11 months after surgery. To the best of our knowledge, this is the first report of a localized mesothelioma in a dog without metastasis/dissemination and highlights the value of mesothelial markers for an accurate diagnosis.(c) 2023 Elsevier Ltd. All rights reserved.
引用
收藏
页码:25 / 29
页数:5
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