B(C6F5)3-catalyzed hydrogermylation of enones: a facile route to germacycles

被引：2

作者：

Xiong, Jiangkun ^{[1
,2
]}

Yan, Maying ^{[1
]}

Jin, Lvnan ^{[1
]}

Song, Weihong ^{[1
]}

Xiao, Lei ^{[1
]}

Xu, Dong ^{[1
]}

Zhai, Chunyang ^{[2
]}

Stephan, Douglas W. ^{[1
,3
]}

Guo, Jing ^{[1
]}

机构：

[1] Ningbo Univ, Inst Drug Discovery Technol, Ningbo, Zhejiang, Peoples R China

[2] Ningbo Univ, Sch Mat Sci & Chem Engn, Ningbo 315211, Peoples R China

[3] Univ Toronto, Dept Chem, 80 St George St, Toronto, ON M5S 3H6, Canada

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年 / 21卷 / 40期

基金：

加拿大自然科学与工程研究理事会;

关键词：

LEWIS PAIR CHEMISTRY; BIOLOGICAL-ACTIVITY; CATALYZED HYDROGERMYLATION; ALKYNES; GERMYLATION;

D O I：

10.1039/d3ob01402a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Organogermacycles are important skeletons for medicinal chemistry and materials. Herein, we reported a B(C6F5)(3) mediated domino hydrogermylation reaction of enones with dihydrogermanes, affording 21 variants of organogermacycle compounds. These germacyclic compounds were obtained in good to excellent yields (up to 99% yield) under mild reaction conditions.

引用

页码：8098 / 8101

页数：4

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