B(C6F5)3-catalyzed hydrogermylation of enones: a facile route to germacycles

被引：2
作者：
Xiong, Jiangkun [1 ,2 ]
Yan, Maying [1 ]
Jin, Lvnan [1 ]
Song, Weihong [1 ]
Xiao, Lei [1 ]
Xu, Dong [1 ]
Zhai, Chunyang [2 ]
Stephan, Douglas W. [1 ,3 ]
Guo, Jing [1 ]
机构：
[1] Ningbo Univ, Inst Drug Discovery Technol, Ningbo, Zhejiang, Peoples R China
[2] Ningbo Univ, Sch Mat Sci & Chem Engn, Ningbo 315211, Peoples R China
[3] Univ Toronto, Dept Chem, 80 St George St, Toronto, ON M5S 3H6, Canada
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年 / 21卷 / 40期
基金：
加拿大自然科学与工程研究理事会;
关键词：
LEWIS PAIR CHEMISTRY; BIOLOGICAL-ACTIVITY; CATALYZED HYDROGERMYLATION; ALKYNES; GERMYLATION;
D O I：
10.1039/d3ob01402a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Organogermacycles are important skeletons for medicinal chemistry and materials. Herein, we reported a B(C6F5)(3) mediated domino hydrogermylation reaction of enones with dihydrogermanes, affording 21 variants of organogermacycle compounds. These germacyclic compounds were obtained in good to excellent yields (up to 99% yield) under mild reaction conditions.
引用
收藏
页码：8098 / 8101
页数：4
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