Two gallstone (Lith) genes, Lith9 and Lith18, produces a synergistic effect in enhancing cholelithogenesis by promoting hepatic secretion of biliary cholesterol in female mice

被引:0
|
作者
Wang, David
Wang, Helen
机构
关键词
lipid transporter; estrogen; lithogenic mechanism; gallstones;
D O I
10.1152/physiol.2023.38.S1.5730554
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
引用
收藏
页数:2
相关论文
共 5 条
  • [1] Lith genes induce biliary cholesterol hypersecretion as a prelude to cholesterol gallstone formation in inbred mice
    Wang, DQH
    Lammert, F
    Paigen, B
    Carey, MC
    GASTROENTEROLOGY, 1997, 112 (04) : A1411 - A1411
  • [2] Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice:: pathophysiology of biliary lipid secretion
    Wang, DQH
    Lammert, F
    Paigen, B
    Carey, MC
    JOURNAL OF LIPID RESEARCH, 1999, 40 (11) : 2066 - 2079
  • [3] Lith genes modify hepatic activities of the major lipid regulatory enzymes during cholesterol gallstone formation in inbred mice.
    Lammert, F
    Wang, DQH
    Paigen, B
    Carey, MC
    GASTROENTEROLOGY, 1997, 112 (04) : A1312 - A1312
  • [4] Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice
    Henning Wittenburg
    Malcolm A. Lyons
    Renhua Li
    Ulrike Kurtz
    Joachim Mössner
    Gary A. Churchill
    Martin C. Carey
    Beverly Paigen
    Mammalian Genome, 2005, 16 : 495 - 504
  • [5] Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice
    Wittenburg, H
    Lyons, MA
    Li, RH
    Kurtz, U
    Mössner, J
    Churchill, GA
    Carey, MC
    Paigen, B
    MAMMALIAN GENOME, 2005, 16 (07) : 495 - 504