On the optimal control of kinetic epidemic models with uncertain social features

被引:3
作者
Franceschi, Jonathan [1 ]
Medaglia, Andrea [1 ]
Zanella, Mattia [1 ]
机构
[1] Univ Pavia, Dept Math F Casorati, Pavia, Italy
关键词
kinetic models; mathematical epidemiology; multi-agent systems; non-pharmaceutical interventions; optimal control; FOKKER-PLANCK EQUATIONS; CONTAINMENT; BEHAVIOR; SPREAD;
D O I
10.1002/oca.3029
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
It is recognized that social heterogeneities in terms of the contact distribution have a strong influence on the spread of infectious diseases. Nevertheless, few data are available on the group composition of social contacts, and their statistical description does not possess universal patterns and may vary spatially and temporally. It is therefore essential to design robust control strategies, mimicking the effects of non-pharmaceutical interventions, to limit efficiently the number of infected cases. In this work, starting from a recently introduced kinetic model for epidemiological dynamics that takes into account the impact of social contacts of individuals, we consider an uncertain contact formation dynamics leading to slim-tailed as well as fat-tailed distributions of contacts. Hence, we analyse the effects of an optimally robust control strategy of the system of agents. Thanks to classical methods of kinetic theory, we couple uncertainty quantification methods with the introduced mathematical model to assess the effects of social limitations. Finally, using the proposed modeling approach and starting from available data, we show the effectiveness of the proposed selective measures to dampen uncertainties together with the epidemic trends.
引用
收藏
页码:494 / 522
页数:29
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