Bioprinting of Cardiac Tissue in Space: Where Are We?

被引:10
作者
Tabury, Kevin [1 ,2 ]
Rehnberg, Emil [1 ,3 ]
Baselet, Bjorn [1 ]
Baatout, Sarah [1 ,3 ]
Moroni, Lorenzo [4 ]
机构
[1] Belgian Nucl Res Ctr, Radiol Unit, Boeretang 200, B-2400 Mol, Belgium
[2] Univ South Carolina, Coll Engn & Comp, Dept Biomed Engn, Columbia, SC 29208 USA
[3] Univ Ghent, Dept Mol Biotechnol, B-9000 Ghent, Belgium
[4] Maastricht Univ, MERLN Inst Technol Inspired Regenerat Med, Dept Complex Tissue Regenerat, Univ Singel 40, NL-6229 ER Maastricht, Netherlands
关键词
bioprinting; bioinks; cardiac tissues; space; CELL; CHALLENGES; SYSTEM; MICROGRAVITY; CONSTRUCT; NETWORKS; BIOINKS; HEART;
D O I
10.1002/adhm.202203338
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Bioprinting in space is the next frontier in tissue engineering. In the absence of gravity, novel opportunities arise, as well as new challenges. The cardiovascular system needs particular attention in tissue engineering, not only to develop safe countermeasures for astronauts in future deep and long-term space missions, but also to bring solutions to organ transplantation shortage. In this perspective, the challenges encountered when using bioprinting techniques in space and current gaps that need to be overcome are discussed. The recent developments that have been made in the bioprinting of heart tissues in space and an outlook on potential future bioprinting opportunities in space are described.
引用
收藏
页数:15
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