Review on the genus Polygonatum polysaccharides: Extraction, purification, structural characteristics and bioactivities

被引：58
作者：
Gong, Huan [1 ,2 ]
Gan, Xiaona [3 ]
Li, Yingzhe [1 ,2 ]
Chen, Jie [1 ,2 ]
Xu, Yongbin [1 ,2 ]
Shi, Songshan [1 ,2 ]
Li, Tingzhao [3 ]
Li, Bo [3 ]
Wang, Huijun [1 ,2 ,4 ]
Wang, Shunchun [1 ,2 ,4 ]
机构：
[1] Shanghai Univ Tradit Chinese Med, Inst Chinese Mat Med, MOE Key Lab Standardizat Chinese Med, Shanghai, Peoples R China
[2] Shanghai Univ Tradit Chinese Med, Inst Chinese Mat Med, SATCM Key Lab New Resources & Qual Evaluat Chinese, Shanghai, Peoples R China
[3] Amway Innovat & Sci Shanghai, 720 Cailun Rd, Shanghai 201203, Peoples R China
[4] Shanghai Univ Tradit Chinese Med, Inst Chinese Mat Med, 1200 Cailun Rd, Shanghai 201203, Peoples R China
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2023年 / 229卷
基金：
中国国家自然科学基金;
关键词：
The genus Polygonatum; Polysaccharides; Structure -activity relationship; SIBIRICUM POLYSACCHARIDE; SIMULTANEOUS DECOLORATION; CYRTONEMA HUA; OLIGOSACCHARIDES; DEPROTEINIZATION; DEGRADATION; MECHANISMS; RHIZOME;
D O I：
10.1016/j.ijbiomac.2022.12.320
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The genus Polygonatum is gaining increasing attention from nutrition experts as well as health-conscious consumers because of its excellent performance in providing nutrients. Among these plants, Polygonatum sibiricum and Polygonatum odoratum have been selected for inclusion in China's Medicinal Food Directory due to their high safety profile. Polysaccharides are considered the main functional component and one of the main active ingredients of the plant. In addition, polysaccharides from genus Polygonatum have a variety of nutritional, biological and health-promoting properties, such as immunomodulatory, anti-inflammatory, cardiovascular protective, neuroprotective, antitumor, antidiabetic, antiosteoporosis, and hepatoprotective properties. This paper reviews the origin, extraction, purification, structural characteristics, biological activity, safety, toxicological evaluation, and structure-activity relationship of polysaccharides from the genus Polygonatum. Ultimately, we hope that this work can provide a more useful reference for understanding the polysaccharide structure and developing of new functional foods from polysaccharides of the genus Polygonatum.
引用
收藏
页码：909 / 930
页数：22
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