Diabetic Sensorimotor Polyneuropathy: An Overview on Epidemiology, Risk Factors, Classification, Diagnosis, and Treatment

被引:2
作者
Anastasiou, Georgia [1 ]
Liberopoulos, Evangelos [2 ]
Tentolouris, Nikolaos [2 ]
Papanas, Nikolaos [3 ]
机构
[1] Univ Ioannina, Fac Med, Dept Internal Med, Ioannina, Greece
[2] Natl & Kapodistrian Univ Athens, Sch Med, Propedeut Dept Med 1, Athens, Greece
[3] Democritus Univ Thrace, Diabet Ctr, Dept Internal Med 2, Diabetic Foot Clin, Alexandroupolis, Greece
关键词
diabetic neuropathy; epidemiology; risk factors; diagnostic testing; treatment; ALPHA-LIPOIC ACID; PERIPHERAL NEUROPATHY; DOUBLE-BLIND; SYMPTOMATIC POLYNEUROPATHY; HYPERTENSION; MULTICENTER; PREVALENCE; PREGABALIN; MELLITUS; STATINS;
D O I
10.1177/15347346241240513
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Diabetic distal symmetric sensorimotor polyneuropathy (DSPN) is a common complication of diabetes with devastating consequences. Hyperglycaemia is the major aetiological factor, while emerging data demonstrate that cardiometabolic risk factors also contribute to its development. Diagnosis of DSPN involves interview of medical and neurological history, foot inspection, and sensory and motor function examination with specific tests such as temperature and pinprick perception for small nerve fibers, and vibration and light touch assessments for large nerve fibers. Management includes optimised glycaemic control, treatment of cardiovascular risk factors, and symptomatic treatment aiming at improving life quality. This article provides an overview on epidemiology, risk factors, classification, diagnosis and current treatment of DSPN.
引用
收藏
页数:12
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