Immunogenicity and safety of quadrivalent inactivated influenza vaccine in children aged 6 to 35 months: A systematic review and meta-analysis

被引：1

作者：

Wei, Xia ^{[1
]}

Tan, Xue ^{[1
]}

Guan, Qinghu ^{[2
]}

Zhang, Ruizhi ^{[2
]}

Lei, Shiguang ^{[1
,2
,3
]}

Wei, Shaofeng ^{[1
]}

机构：

[1] Guizhou Med Univ, Sch Publ Hlth, Key Lab Environm Pollut Monitoring & Dis Control, Minist Educ, Guiyang, Guizhou, Peoples R China

[2] Guizhou Prov Ctr Dis Control & Prevent, Guiyang, Guizhou, Peoples R China

[3] Guizhou Prov Ctr Dis Control & Prevent, 101 Bageyan Rd, Guiyang 550004, Guizhou, Peoples R China

来源：

HUMAN VACCINES & IMMUNOTHERAPEUTICS | 2023年 / 19卷 / 02期

关键词：

Random clinical trials; children aged 6 to 35 months; immunogenicity; safety; systematic review; influenza vaccine; SEASONAL INFLUENZA; COST-EFFECTIVENESS; CONTROLLED-TRIAL; DOUBLE-BLIND; PHASE-III; HONG-KONG; RECOMMENDATIONS; SURVEILLANCE; IMMUNIZATION; EFFICACY;

D O I：

10.1080/21645515.2023.2256510

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Evidence of the immunogenicity and safety of quadrivalent inactivated influenza vaccine in children aged 6 to 35 months has been emerging. To evaluate the immunogenicity and safety of quadrivalent inactivated influenza vaccine in children aged 6 to 35 months in a systematic review and meta-analysis. This meta-analysis included 12 studies with 6722 participants receiving QIV, 3575 participants receiving TIV, 4249 participants receiving full-dose QIV (F-QIV), and 3722 participants receiving half-dose QIV (H-QIV). Among children aged 6 to 35 months, QIV produces a better Immunogenicity against influenza B vaccine strains not contained in TIV. However, injection site reaction was more common for QIV, F-QIV showed superior efficacy for the B lineage, but fever and injection site pain was more frequently reported for F-QIV than H-QIV. These data support the immunogenicity and safety of quadrivalent inactivated influenza vaccine among children aged 6 to 35 months.

引用

页数：13

共 44 条

[1] The rationale for quadrivalent influenza vaccines [J].

Ambrose, Christopher S. ;

Levin, Myron J. .

HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2012, 8 (01) :81-88

[2] Efficacy of live attenuated influenza vaccine in children against influenza B viruses by lineage and antigenic similarity [J].

Belshe, Robert B. ;

Coelingh, Kathleen ;

Ambrose, Christopher S. ;

Woo, Jennifer C. ;

Wu, Xionghua .

VACCINE, 2010, 28 (09) :2149-2156

[3] Updates on Influenza Vaccination in Children [J].

Campbell, Angela J. P. ;

Grohskopf, Lisa A. .

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2018, 32 (01) :75-+

[4] Influenza B Lineage Circulation and Hospitalization Rates in a Subtropical City, Hong Kong, 2000-2010 [J].

Chan, Paul K. S. ;

Chan, Martin C. W. ;

Cheung, Jo L. K. ;

Lee, Nelson ;

Leung, Ting F. ;

Yeung, Apple C. M. ;

Wong, Martin C. S. ;

Ngai, Karry L. K. ;

Nelson, E. Anthony S. ;

Hui, David S. C. .

CLINICAL INFECTIOUS DISEASES, 2013, 56 (05) :677-684

[5] Active-controlled phase III study of an egg-cultivated quadrivalent inactivated split-virion influenza vaccine (GC3110A) in healthy Korean children aged 6-35 months [J].

Choi, Ui Yoon ;

Kim, Ki Hwan ;

Lee, Kyung Yil ;

Kim, Jong-Hyun ;

Kim, Chun Soo ;

Eun, Byung Wook ;

Kim, Hwang Min ;

Kim, Dong Ho ;

Song, Song Eun ;

Jo, Dae Sun ;

Lee, Jin ;

Ma, Sang Hyuk ;

Kim, Kwang Nam ;

Kang, Jin Han .

VACCINE, 2021, 39 (15) :2103-2109

[6] Quadrivalent Influenza Vaccine Prevents Illness and Reduces Healthcare Utilization Across Diverse Geographic Regions During Five Influenza Seasons A Randomized Clinical Trial [J].

Dbaibo, Ghassan ;

Amanullah, Arshad ;

Claeys, Carine ;

Izu, Allen ;

Jain, Varsha K. ;

Kosalaraksa, Pope ;

Rivera, Luis ;

Soni, Jyoti ;

Yanni, Emad ;

Zaman, Khalequ ;

Acosta, Beatriz ;

Ariza, Miguel ;

Basanta, Maria L. Arroba ;

Bavdekar, Ashish ;

Carmona, Alfonso ;

Cousin, Luis ;

Danier, Jasur ;

Diaz, Alfonso ;

Diez-Domingo, Javier ;

Dinleyici, Ener C. ;

Faust, Saul N. ;

Garcia-Sicilia, Jose ;

Gomez-Go, Grace D. ;

Gonzales, Maria L. A. ;

Hacimustafaoglu, Mustafa ;

Hughes, Stephen M. ;

Jackowska, Teresa ;

Kant, Shashi ;

Lucero, Marilla ;

Bermudez, Josep Mares ;

Martinon-Torres, Federico ;

Montellano, May ;

Prymula, Roman ;

Puthanakit, Thanyawee ;

Ruzkova, Renata ;

Sadowska-Krawczenko, Iwona ;

Szymanski, Henryk ;

Ulied, Angels ;

Woo, Wayne ;

Schuind, Anne ;

Innis, Bruce L. .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2020, 39 (01) :E1-E10

[7] Efficacy and safety of a quadrivalent influenza vaccine in children aged 6-35 months: A global, multiseasonal, controlled, randomized Phase III study [J].

Esposito, Susanna ;

Nauta, Jos ;

Lapini, Giulia ;

Montomoli, Emanuele ;

van de Witte, Serge .

VACCINE, 2022, 40 (18) :2626-2634

[8]

Eun BW, 2019, PEDIATR INFECT DIS J, V38, pE209, DOI [10.1097/INF.0000000000002406, 10.1097/inf.0000000000002406]

[9]

Fiore A., 2010, Prevention and control of seasonal influenza with vaccines: recommendations of the advisory committee on immunization practices (ACIP), 2010

[10] Seasonal influenza: The burden of disease in children [J].

Fraaij, Pieter L. A. ;

Heikkinen, Terho .

VACCINE, 2011, 29 (43) :7524-7528

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