Intramolecular [2+2] Cycloaddition of Isocarbostyrils Catalyzed by an Iridium Visible-Light Photocatalyst

被引：4

作者：

Arai, Noriyoshi ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Engn, Div Appl Chem, Sapporo, Hokkaido 0608628, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 07期

关键词：

ISOQUINOLINE ALKALOIDS; PHOTOCYCLOADDITION; ACCESS; RING; TRANSFORMATIONS; DERIVATIVES; ELECTRON; ROUTE;

D O I：

10.1021/acs.joc.3c00059

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Irradiation on N-(omega-alkenyl)isocarbostyrils in the presence of an iridium photocatalyst by LEDs emitting 455 nm light gave the corresponding cyclobutane-fused benzo[b]quinolizine derivatives stereoselectively in high yields. Loading 1 mol % of the catalyst was enough to obtain high yields of the products in convenient reaction time in many cases. The reaction likely proceeds through stepwise [2 + 2] cycloaddition via a triplet biradical intermediate.

引用

页码：4848 / 4853

页数：6

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