The Impact of Free Sugar on Human Health-A Narrative Review

被引：55
作者：
Gillespie, Kerri M. [1 ]
Kemps, Eva [2 ]
White, Melanie J. [3 ]
Bartlett, Selena E. [1 ]
机构：
[1] Queensland Univ Technol, Fac Hlth, Sch Clin Sci, Kelvin Grove, Qld 4059, Australia
[2] Flinders Univ S Australia, Coll Educ Psychol & Social Work, Bedford Pk, SA 5042, Australia
[3] Queensland Univ Technol, Fac Hlth, Sch Psychol & Counselling, Kelvin Grove, Qld 4059, Australia
来源：
NUTRIENTS | 2023年 / 15卷 / 04期
基金：
英国医学研究理事会; 澳大利亚研究理事会;
关键词：
sugar; high-fructose corn syrup; fructose; sugar-sweetened beverage; cognition; obesity; coronary heart disease; diabetes; microbiome; neuroinflammation; SWEETENED BEVERAGE CONSUMPTION; DOSE-RESPONSE METAANALYSIS; TYPE-2; DIABETES-MELLITUS; SOFT DRINK CONSUMPTION; CORONARY-HEART-DISEASE; FRUCTOSE CORN SYRUP; HIGH SUCROSE CONSUMPTION; COGNITIVE PERFORMANCE; GLUCOSE REGULATION; CARBOHYDRATE INTAKE;
D O I：
10.3390/nu15040889
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
The importance of nutrition in human health has been understood for over a century. However, debate is ongoing regarding the role of added and free sugars in physiological and neurological health. In this narrative review, we have addressed several key issues around this debate and the major health conditions previously associated with sugar. We aim to determine the current evidence regarding the role of free sugars in human health, specifically obesity, diabetes, cardiovascular diseases, cognition, and mood. We also present some predominant theories on mechanisms of action. The findings suggest a negative effect of excessive added sugar consumption on human health and wellbeing. Specific class and source of carbohydrate appears to greatly influence the impact of these macronutrients on health. Further research into individual effects of carbohydrate forms in diverse populations is needed to understand the complex relationship between sugar and health.
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页数：25
相关论文
共 235 条
[1]   Effects of caffeine and glucose, alone and combined, on cognitive performance [J].
Adan, Ana ;
Maria Serra-Grabulosa, Josep .
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 2010, 25 (04) :310-317
[2]   Insulin resistance is a cardiovascular risk factor in humans [J].
Adeva-Andany, Maria M. ;
Martinez-Rodriguez, Julia ;
Gonzalez-Lucan, Manuel ;
Fernandez-Fernandez, Carlos ;
Castro-Quintela, Elvira .
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, 2019, 13 (02) :1449-1455
[3]   Dietary intake of carbohydrates and risk of type 2 diabetes: the European Prospective Investigation into Cancer-Norfolk study [J].
Ahmadi-Abhari, Sara ;
Luben, Robert N. ;
Powell, Natasha ;
Bhaniani, Amit ;
Chowdhury, Rajiv ;
Wareham, Nicholas J. ;
Forouhi, Nita G. ;
Khaw, Kay-Tee .
BRITISH JOURNAL OF NUTRITION, 2014, 111 (02) :342-352
[4]   Free and Added Sugar Consumption and Adherence to Guidelines: The UK National Diet and Nutrition Survey (2014/15-2015/16) [J].
Amoutzopoulos, Birdem ;
Steer, Toni ;
Roberts, Caireen ;
Collins, David ;
Page, Polly .
NUTRIENTS, 2020, 12 (02)
[5]   Adiposity among 132 479 UK Biobank participants; contribution of sugar intake vs other macronutrients [J].
Anderson, J. J. ;
Celis-Morales, C. A. ;
Mackay, D. F. ;
Iliodromiti, S. ;
Lyall, D. M. ;
Sattar, N. ;
Gill, J. M. R. ;
Pell, J. P. .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2017, 46 (02) :492-501
[6]  
[Anonymous], Overweight and Obesity
[7]  
[Anonymous], 2015, GUIDELINE SUGARS INT
[8]  
[Anonymous], 2017, TRENDS CARDIOVASCULA
[9]  
[Anonymous], Obesity and overweight
[10]   Falsehoods and facts about dietary sugars: a call for evidence-based policy [J].
Archer, Edward ;
Arjmandi, Bahram .
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2021, 61 (22) :3725-3739
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